Histacet 5 mg/5 ml (Syrup)
50 ml bottle: ৳ 15.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Medimet pharmaceuticals ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal & perennial allergic rhinitis
- Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria and allergen induced asthma
Pharmacology
- Potent H1 receptor antagonist
- No significant anticholinergic and antiserotonic effects
- Inhibition of histamine-mediated early phase of allergic reaction
- Reduction of migration of inflammatory cells
- Reduction of release of mediators associated with late phase of allergic reaction
- Peak plasma concentrations achieved within one hour of administration
- Plasma half-life of approximately 11 hours
- Renal clearance of 30 ml/minute
Dosage & Administration
- Adult dosage: 1 tablet or 2 teaspoonfuls daily
- Dosage for children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoonful twice daily
- Injectable dosage form for intravenous administration
- Recommended dosage for adults and adolescents 12 years of age and older: 10 mg administered by intravenous injection
Interaction
- No clinically significant drug interactions with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, or Erythromycin
Contraindications
- Hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- Common side effect: somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category: B
- Use during pregnancy only if clearly needed
- Excretion in human milk
- Caution when administered to a nursing woman
Precautions & Warnings
- Caution when driving a car or operating heavy machinery
Use in Special Populations
- Reduced clearance in patients with mild to moderate hepatic and renal impairment
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Reduced clearance in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children