Lipiles 20 mg (Tablet)

Unit Price: ৳ 18.00 (1 x 10: ৳ 180.00)
Strip Price: ৳ 180.00

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Pharmasia limited
Also available as
Lipiles 10 mg tablet

ProductTitle

Lipiles 20 mg Tablet

Categories

  • Medicine
  • Pharmaceuticals
  • Cholesterol Management

Description

Lipiles 20 mg Tablet is a selective inhibitor of HMG-CoA reductase indicated as an adjunct to diet to reduce elevated cholesterol levels. It is used for the treatment of hypercholesterolaemia, dyslipidemia, and prevention of cardiovascular events.

Dimensions

  • Tablet Size: 20 mg

ColorOptions

  • White

Functions

  • Reduces total cholesterol and LDL cholesterol levels
  • Increases hepatic LDL receptors for enhanced uptake of LDL
  • Lowers triglycerides and apolipoprotein B levels

Materials

  • Active Ingredient: Atorvastatin
  • Chemical Structure: C33H35FN2O5

TechnicalSpecifications

  • Rapidly absorbed after oral administration
  • Increases in absorption proportionate to dose
  • Volume of distribution: approximately 381 liters
  • Systemic availability of HMG-CoA reductase inhibitory activity: approximately 30%
  • Metabolized by cytochrome P450 3A4
  • Plasma elimination half-life: approximately 14 hours

DesignElements

  • Selective inhibitor of HMG-CoA reductase
  • Chemical structure

UsabilityFeatures

  • Once daily administration
  • Can be taken with or without food
  • Recommended starting dose: 10 or 20 mg once daily
  • Dosage range: 10 to 80 mg once daily
  • Dosing adjustments based on lipid levels
  • Indicated for adults and children (10-18 years)
  • Can be taken for long-term use

Contraindications

  • Hypersensitivity to any component of the medication
  • Active liver disease
  • Unexplained persistent elevations of serum transaminases
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

SideEffects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

PregnancyAndLactation

  • Contraindicated during pregnancy
  • Safety not established in pregnant women
  • Not to be used by breastfeeding women

PrecautionsAndWarnings

  • Liver function tests recommended before initiation of treatment
  • Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected

SpecialPopulations

  • Greater degree of LDL-lowering in elderly patients
  • No pediatric pharmacokinetic data available
  • No clinically significant gender difference in LDL-C reduction
  • No influence of renal disease on plasma concentrations or LDL-C reduction
  • Markedly increased plasma concentrations in patients with chronic alcoholic liver disease

OverdoseEffects

  • Specific treatment not available
  • Liver function tests and serum CK level monitoring recommended

TherapeuticClass

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

StorageConditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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