No-Trol 10 mg (Tablet)
Unit Price: ৳ 1.50 (10 x 10: ৳ 150.00)
Strip Price: ৳ 15.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Aexim pharmaceuticals ltd |
Indications
- Relief of symptoms associated with seasonal & perennial allergic rhinitis
- Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
- Treatment of allergen induced asthma
Pharmacology
- Potent H1 receptor antagonist
- No significant anticholinergic and antiserotonic effects
- Inhibits histamine-mediated early phase of allergic reaction
- Reduces migration of inflammatory cells and release of mediators
- Peak plasma concentrations of 257 mcg/L within one hour of administration
- Plasma half-life of approximately 11 hours
Dosage & Administration
- Adult dosage: 1 tablet or 2 teaspoonfuls daily
- Children 2-6 years dosage: 1 teaspoonful once daily
- Children 6 months to 2 years dosage: 1/2 teaspoonful once daily
- Recommended dosage for injectable form in adults and adolescents
- Recommended dosage for injectable form in children 6 months to 11 years
Interaction
- No clinically significant drug interactions with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, or Erythromycin
Contraindications
- History of hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- Most common side effect is somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Excreted in human milk
- Caution during pregnancy and lactation
Precautions & Warnings
- Caution when driving a car or operating heavy machinery
Use in Special Populations
- Total body clearance reduced in patients with mild to moderate hepatic and renal impairment
- Pediatric safety demonstrated in patients aged 6 months to 5 years
- Clearance reduced in elderly patients in proportion to decrease in creatinine clearance
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children