Ontin 5 mg/5 ml (Syrup)

60 ml bottle: ৳ 35.00

Medicine Details

Indications

  • Relief of symptoms associated with seasonal allergic rhinitis
  • Relief of symptoms associated with perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen induced asthma

Pharmacology

  • Cetirizine Hydrochloride is a potent H1 receptor antagonist
  • Does not cause significant anticholinergic effects
  • Inhibits histamine-mediated early phase of allergic reaction
  • Reduces migration of inflammatory cells
  • Reduces release of mediators associated with late phase of allergic reaction
  • Plasma half-life of approximately 11 hours

Dosage & Administration

  • Recommended daily dosage for adults and children 6 years and older
  • Recommended daily dosage for children 2-6 years
  • Recommended daily dosage for children 6 months to 2 years
  • Injectable dosage form for intravenous administration
  • Recommended dosage for adults and adolescents 12 years of age and older for injectable form
  • Recommended dosage for children 6 to 11 years of age for injectable form
  • Recommended dosage for children 6 months to 5 years of age for injectable form

Interaction

  • No clinically significant drug interactions with Theophylline
  • No clinically significant drug interactions with Azithromycin
  • No clinically significant drug interactions with Pseudoephedrine
  • No clinically significant drug interactions with Ketoconazole
  • No clinically significant drug interactions with Erythromycin

Contraindications

  • Contraindicated in patients with hypersensitivity to Cetirizine
  • Contraindicated in patients with hypersensitivity to hydroxyzine

Side Effects

  • Most common side effect: somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category: B
  • Use during pregnancy only if clearly needed
  • Caution when administering to a nursing woman

Precautions & Warnings

  • Caution when driving or operating heavy machinery

Use in Special Populations

  • Reduced clearance and increased AUC in patients with mild to moderate hepatic and renal impairment
  • Safety demonstrated in pediatric patients aged 6 months to 5 years
  • Reduced clearance in elderly patients

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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