Opzin 5 mg/5 ml (Syrup)
60 ml bottle: ৳ 22.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Pharmadesh laboratories ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal & perennial allergic rhinitis
- Treatment of the skin manifestations of chronic idiopathic urticaria
- Treatment of allergen induced asthma
Pharmacology
- Potent H1 receptor antagonist
- No significant anticholinergic and antiserotonic effects
- Inhibition of histamine-mediated early phase of allergic reaction
- Reduction of migration of inflammatory cells and release of mediators
- Peak plasma concentrations of 257 mcg/L within one hour of administration
- Renal clearance of 30 ml/minute
- Plasma half-life of approximately 11 hours
Dosage & Administration
- Adult dosage: 1 tablet or 2 teaspoonfuls daily
- Children 2-6 years: 1 teaspoonful once daily
- Children 6 months to 2 years: 1/2 teaspoonful once daily
- Injectable dosage for adults and adolescents: 10 mg intravenously
Interaction
- No clinically significant drug interactions with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, or Erythromycin
Contraindications
- History of hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- Common side effect: somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Excretion in human milk
- Caution advised during nursing
Precautions & Warnings
- Caution advised when driving or operating heavy machinery
Use in Special Populations
- Reduced clearance in patients with hepatic or renal insufficiency
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Reduced clearance in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children