Orgy 10 mg (Tablet)

Unit Price: ৳ 3.00 (10 x 14: ৳ 420.00)
Strip Price: ৳ 42.00

Medicine Details

Category Details
Generic Cetirizine hydrochloride
Company Kumudini pharma ltd
Also available as

Indications

  • Relief of symptoms associated with seasonal & perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Relief of symptoms of allergen-induced asthma

Pharmacology

  • Potent H1 receptor antagonist
  • No significant anticholinergic and antiserotonic effects
  • Inhibition of histamine-mediated early phase of allergic reaction
  • Reduction of migration of inflammatory cells and release of mediators associated with late phase of allergic reaction
  • Peak plasma concentrations of 257 mcg/L within one hour of administration
  • Plasma half-life of approximately 11 hours
  • Renal clearance of 30 ml/minute
  • Excretion half-life of approximately nine hours

Dosage & Administration

  • Adults and Children 6 years and older: 1 tablet or 2 teaspoonfuls daily
  • Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoonful twice daily
  • Children 6 months to 2 years : 1/2 teaspoonful once daily
  • Recommended dosage regimen for injectable form in adults and adolescents 12 years of age and older is 10 mg administered by intravenous injection

Interaction

  • No clinically significant drug interactions found

Contraindications

  • History of hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Most common side effect: somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Excretion in human milk
  • Caution advised when administered to a nursing woman

Precautions & Warnings

  • Caution advised when driving a car or operating heavy machinery

Use in Special Populations

  • Caution in patients with hepatic or renal insufficiency
  • Safety demonstrated in pediatric patients aged 6 months to 5 years
  • Reduction in clearance in elderly patients

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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