Orgy 5 mg/5 ml (Syrup)

60 ml bottle: ৳ 25.00

Medicine Details

Category Details
Generic Cetirizine hydrochloride
Company Kumudini pharma ltd
Also available as

Indications

  • Relief of symptoms associated with seasonal & perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen induced asthma

Pharmacology

  • Potent H1 receptor antagonist
  • No significant anticholinergic and antiserotonic effects
  • Inhibits histamine-mediated early phase of allergic reaction
  • Reduces migration of inflammatory cells
  • Reduces release of mediators associated with late phase of allergic reaction
  • Peak plasma concentration of Cetirizine 10 mg
  • Plasma half-life of approximately 11 hours
  • Renal clearance of 30 ml/minute
  • Excretion half-life of approximately nine hours

Dosage & Administration

  • Recommended dosage for adults and children 6 years and older
  • Recommended dosage for children 2-6 years
  • Recommended dosage for children 6 months to 2 years
  • Single use injectable product for intravenous administration
  • Recommended dosages for adults, adolescents, and children 6 months to 11 years for injectable form of Cetirizine

Interaction

  • No clinically significant drug interactions found with Theophylline
  • No clinically significant drug interactions found with Azithromycin
  • No clinically significant drug interactions found with Pseudoephedrine
  • No clinically significant drug interactions found with Ketoconazole
  • No clinically significant drug interactions found with Erythromycin

Contraindications

  • Contraindicated in patients with a history of hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Most common side effect: somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category: B
  • No adequate and well-controlled studies in pregnant women
  • Excretion in human milk
  • Caution during administration to nursing women

Precautions & Warnings

  • Caution when driving a car or operating heavy machinery

Use in Special Populations

  • Reduction in total body clearance in patients with hepatic or renal insufficiency
  • Safety demonstrated in pediatric patients aged 6 months to 5 years
  • Reduction in clearance in elderly patients

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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