Riz 5 mg/5 ml (Syrup)
60 ml bottle: ৳ 25.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Orion pharma ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal & perennial allergic rhinitis
- Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
- Treatment of allergen-induced asthma
Pharmacology
- Cetirizine Hydrochloride is a potent H1 receptor antagonist
- No significant anticholinergic and antiserotonic effects
- Inhibits histamine-mediated early phase of allergic reaction
- Reduces migration of inflammatory cells
- Reduces release of mediators associated with late phase of allergic reaction
- Peak plasma concentrations achieved within one hour of administration
- Plasma half-life is approximately 11 hours
- Renal clearance is 30 ml/minute
- Consistent absorption from one subject to the next
Dosage & Administration
- Dosage for adults, children 6 years and older, and children 2-6 years
- Dosage for children 6 months to 2 years
- Dosage for adults and adolescents 12 years of age and older
- Dosage for children 6 to 11 years of age
- Dosage for children 6 months to 5 years of age
- Recommended dosage regimen for treatment of acute urticaria
- Administer Cetirizine as an intravenous push over a period of 1 to 2 minutes
Interaction
- No clinically significant drug interactions found with Theophylline
- No clinically significant drug interactions found with Azithromycin
- No clinically significant drug interactions found with Pseudoephedrine
- No clinically significant drug interactions found with Ketoconazole
- No clinically significant drug interactions found with Erythromycin
Contraindications
- Contraindicated in patients with history of hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- Most common side effect is somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category of Cetirizine Hydrochloride is B
- No adequate and well-controlled studies in pregnant women
- Cetirizine Hydrochloride excreted in human milk
Precautions & Warnings
- Caution should be exercised when driving a car or operating heavy machinery
Use in Special Populations
- Total body clearance reduced in patients with mild to moderate hepatic and renal impairment
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children