Rizin 10 mg (Tablet)
Unit Price: ৳ 2.51 (10 x 10: ৳ 251.00)
Strip Price: ৳ 25.10
Medicine Details
Category | Details |
---|---|
Generic | Cetirizine hydrochloride |
Company | Gaco pharmaceuticals ltd |
Also available as |
Indications
- Relief of symptoms associated with seasonal & perennial allergic rhinitis
- Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
- Treatment of allergen-induced asthma
Pharmacology
- Potent H1 receptor antagonist
- No significant anticholinergic and antiserotonic effects
- Histamine-mediated early phase inhibition
- Reduction of inflammatory cell migration
- Reduction of mediators associated with the late phase of allergic reaction
- Peak plasma concentrations of 257 mcg/L within one hour of administration
- Plasma half-life of approximately 11 hours
- Renal clearance of 30 ml/minute
Dosage & Administration
- Dosage form: oral and injectable
- Recommended dosage for adults and children
- Different dosage recommendations for different age groups
Interaction
- No clinically significant drug interactions with specific drugs
Contraindications
- Contraindicated in patients with history of hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- Common side effect is somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category B
- No adequate and well-controlled studies in pregnant women
- Excretion in human milk
Precautions & Warnings
- Caution when driving or operating heavy machinery
Use in Special Populations
- Reduced total body clearance in hepatic and renal insufficiency
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Reduced clearance in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children