Rizin 10 mg (Tablet)

Unit Price: ৳ 2.51 (10 x 10: ৳ 251.00)
Strip Price: ৳ 25.10

Medicine Details

Category Details
Generic Cetirizine hydrochloride
Company Gaco pharmaceuticals ltd
Also available as

Indications

  • Relief of symptoms associated with seasonal & perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen-induced asthma

Pharmacology

  • Potent H1 receptor antagonist
  • No significant anticholinergic and antiserotonic effects
  • Histamine-mediated early phase inhibition
  • Reduction of inflammatory cell migration
  • Reduction of mediators associated with the late phase of allergic reaction
  • Peak plasma concentrations of 257 mcg/L within one hour of administration
  • Plasma half-life of approximately 11 hours
  • Renal clearance of 30 ml/minute

Dosage & Administration

  • Dosage form: oral and injectable
  • Recommended dosage for adults and children
  • Different dosage recommendations for different age groups

Interaction

  • No clinically significant drug interactions with specific drugs

Contraindications

  • Contraindicated in patients with history of hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Common side effect is somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • No adequate and well-controlled studies in pregnant women
  • Excretion in human milk

Precautions & Warnings

  • Caution when driving or operating heavy machinery

Use in Special Populations

  • Reduced total body clearance in hepatic and renal insufficiency
  • Safety demonstrated in pediatric patients aged 6 months to 5 years
  • Reduced clearance in elderly patients

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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