Sartec 5 mg/5 ml (Syrup)
60 ml bottle: ৳ 20.06
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Rangs pharmaceuticals ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal allergic rhinitis
- Relief of symptoms associated with perennial allergic rhinitis
- Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
- Treatment of allergen-induced asthma
Pharmacology
- Potent H1 receptor antagonist
- No significant anticholinergic and antiserotonic effects
- Inhibition of histamine-mediated early phase of allergic reaction
- Reduction of migration of inflammatory cells and release of mediators in late phase of allergic reaction
- Peak plasma concentration of 257 mcg/L within one hour of administration
- Plasma half-life of approximately 11 hours
- Renal clearance of 30 ml/minute
- Excretion half-life of approximately nine hours
Dosage & Administration
- Dosage for adults and children 6 years and older: 1 tablet or 2 teaspoonfuls daily
- Dosage for children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoonful twice daily
- Injectable dosage form for adults and adolescents 12 years of age and older: 10 mg administered by intravenous injection
- Injectable dosage form for children 6 to 11 years of age: 5 mg or 10 mg administered by intravenous injection depending on symptom severity
- Injectable dosage form for children 6 months to 5 years of age: 2.5 mg administered by intravenous injection
Interaction
- No clinically significant drug interactions with Theophylline
- No clinically significant drug interactions with Azithromycin
- No clinically significant drug interactions with Pseudoephedrine
- No clinically significant drug interactions with Ketoconazole
- No clinically significant drug interactions with Erythromycin
Contraindications
- Contraindicated in patients with history of hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- Most common side effect is somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category B
- No adequate and well-controlled studies in pregnant women
- Cetirizine Hydrochloride excreted in human milk
- Caution advised during lactation
Precautions & Warnings
- Caution advised when driving a car or operating heavy machinery
Use in Special Populations
- Reduction in clearance and increase in AUC and half-life in patients with mild to moderate hepatic and renal impairment
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Reduction in clearance in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children