Setir 10 mg (Tablet)
Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Amulet pharmaceuticals ltd |
Indications
- Relief of symptoms associated with seasonal & perennial allergic rhinitis
- Treatment of skin manifestations of chronic idiopathic urticaria
- Treatment of allergen induced asthma
Pharmacology
- Potent H1 receptor antagonist
- Does not cause significant anticholinergic and antiserotonic effects
- Inhibits histamine-mediated early phase of allergic reaction
- Reduces migration of inflammatory cells
- Reduces release of mediators associated with late phase of allergic reaction
- Peak plasma concentrations of 257 mcg/L achieved within one hour of administration
- Plasma half-life of approximately 11 hours
Dosage & Administration
- Adult dose: 1 tablet or 2 teaspoonfuls daily
- Doses for children based on age
- Recommended dosage regimen for injectable form based on age
- Not recommended for pediatric patients less than 6 years of age with impaired renal or hepatic function
Interaction
- No clinically significant drug interactions found with specific drugs
Contraindications
- Contraindicated in patients with hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- Common side effect: somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category: B
- Caution should be exercised during pregnancy and lactation
Precautions & Warnings
- Caution should be exercised when driving or operating machinery
Use in Special Populations
- Total body clearance reduced in patients with mild to moderate hepatic and renal impairment
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Clearance reduced in elderly patients in proportion to decrease in creatinine clearance
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children