Sytrol 10 mg (Tablet)

Unit Price: ৳ 2.50 (100's pack: ৳ 250.00)

Medicine Details

Category Details
Generic Cetirizine hydrochloride
Company Mst pharma
Also available as

Indications

  • Seasonal allergic rhinitis relief
  • Perennial allergic rhinitis relief
  • Chronic idiopathic urticaria treatment
  • Allergen induced asthma treatment

Pharmacology

  • H1 receptor antagonist
  • Antihistamine
  • Histamine-mediated allergy reaction inhibition
  • Reduction of inflammatory cells migration
  • Reduction of allergic reaction mediators release
  • Plasma concentration: 257 mcg/L (adults), 980 mcg/L (children)
  • Peak blood levels: 0.3 micrograms/ml
  • Plasma half-life: approximately 11 hours
  • Renal clearance: 30 ml/minute
  • Excretion half-life: approximately 9 hours

Dosage & Administration

  • Adult dosage: 1 tablet or 2 teaspoonfuls daily
  • Children 2-6 years dosage: 1 teaspoonful once daily or 1/2 teaspoonful twice daily
  • Children 6 months to 2 years dosage: 1/2 teaspoonful once daily
  • Recommended injectable dosage: 10 mg for adults and adolescents
  • Storage conditions: Keep in a dry place away from light and heat. Keep out of the reach of children

Interaction

  • No clinically significant drug interactions with Theophylline
  • No clinically significant drug interactions with Azithromycin
  • No clinically significant drug interactions with Pseudoephedrine
  • No clinically significant drug interactions with Ketoconazole
  • No clinically significant drug interactions with Erythromycin

Contraindications

  • Contraindicated in patients with hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Most common side effect: somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category: B
  • Excreted in human milk
  • Caution during pregnancy and lactation

Precautions & Warnings

  • Caution when driving or operating heavy machinery

Use in Special Populations

  • Reduced clearance in elderly patients
  • Reduced clearance in patients with hepatic or renal insufficiency
  • Safety demonstrated in pediatric patients aged 6 months to 5 years

Therapeutic Class

  • Sedating Anti-histamine

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