Trin 5 mg/5 ml (Syrup)

60 ml bottle: ৳ 28.75

Medicine Details

Category Details
Generic Cetirizine hydrochloride
Company Globe pharmaceuticals ltd
Also available as

Indications

  • Relief of symptoms associated with seasonal & perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen induced asthma

Pharmacology

  • H1 receptor antagonist
  • No significant anticholinergic and antiserotonic effects
  • Inhibits histamine-mediated allergic reaction
  • Reduces inflammation and mediators
  • Peak plasma concentrations achieved within one hour
  • Plasma half-life approximately 11 hours
  • Consistent absorption across subjects
  • Renal clearance and excretion half-life

Dosage & Administration

  • Oral dosage for adults and children 6 years and older
  • Oral dosage for children 2-6 years and 6 months to 2 years
  • Injectable dosage for adults, adolescents and children 6 months to 11 years

Interaction

  • No clinically significant drug interactions with specific drugs

Contraindications

  • Hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Use during pregnancy only if clearly needed
  • Excreted in human milk

Precautions & Warnings

  • Caution when driving or operating heavy machinery

Use in Special Populations

  • Reduced clearance in patients with hepatic or renal insufficiency
  • Safety demonstrated in pediatric patients aged 6 months to 5 years
  • Reduced clearance in elderly patients

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in dry place away from light and heat
  • Keep out of the reach of children

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