Rinzin 10 mg (Tablet)

Unit Price: ৳ 3.00 (100's pack: ৳ 300.00)

Medicine Details

Indications

  • Relief of symptoms associated with seasonal allergic rhinitis
  • Relief of symptoms associated with perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen induced asthma

Pharmacology

  • Potent H1 receptor antagonist
  • No significant anticholinergic and antiserotonic effects
  • Inhibition of histamine-mediated early phase of allergic reaction
  • Reduction of migration of inflammatory cells and release of mediators associated with late phase of allergic reaction
  • Plasma half-life of approximately 11 hours
  • Renal clearance of 30 ml/minute

Dosage & Administration

  • Dosage form: oral tablet and injectable
  • Different dosages for adults and children aged 6 years and older
  • Different dosages for children aged 2-6 years
  • Different dosages for children aged 6 months to 2 years
  • Injectable dosage for adults, adolescents, and children aged 6 months to 11 years

Interaction

  • No clinically significant drug interactions with Theophylline
  • No clinically significant drug interactions with Azithromycin
  • No clinically significant drug interactions with Pseudoephedrine
  • No clinically significant drug interactions with Ketoconazole
  • No clinically significant drug interactions with Erythromycin

Contraindications

  • Contraindicated in patients with hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Common side effect: somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category: B
  • Cetirizine excreted in human milk
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Caution required when driving a car or operating heavy machinery

Use in Special Populations

  • Reduced clearance and increased AUC in patients with hepatic or renal insufficiency
  • Safety demonstrated in pediatric patients aged 6 months to 5 years

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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