Noriz 5 mg/5 ml (Syrup)
60 ml bottle: ৳ 16.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Skylab pharmaceuticals ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal allergic rhinitis
- Relief of symptoms associated with perennial allergic rhinitis
- Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
- Treatment of allergen-induced asthma
Pharmacology
- Potent H1 receptor antagonist
- No significant anticholinergic effects
- No significant antiserotonic effects
- Inhibits histamine-mediated early phase of allergic reaction
- Reduces migration of inflammatory cells
- Reduces release of mediators associated with late phase of allergic reaction
- Peak plasma concentrations achieved within one hour
- Plasma half-life of approximately 11 hours
- Renal clearance of 30 ml/minute
- Excretion half-life of approximately nine hours
Dosage & Administration
- Adult dosage: 1 tablet or 2 teaspoonfuls daily
- Pediatric dosage: Varies by age
- Single use injectable product for intravenous administration only
- Intravenous push over a period of 1 to 2 minutes
- Dosage not recommended in pediatric patients less than 6 years of age with impaired renal or hepatic function
Interaction
- No clinically significant drug interactions with Theophylline
- No clinically significant drug interactions with Azithromycin
- No clinically significant drug interactions with Pseudoephedrine
- No clinically significant drug interactions with Ketoconazole
- No clinically significant drug interactions with Erythromycin
- No clinically significant interactions with other drugs
Contraindications
- Contraindicated in patients with hypersensitivity to Cetirizine
- Contraindicated in patients with hypersensitivity to hydroxyzine
Side Effects
- Most common side effect: Somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category: B
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if clearly needed
- Cetirizine excreted in human milk
- Caution advised when administering to nursing women
Precautions & Warnings
- Caution advised when driving or operating heavy machinery
Use in Special Populations
- Total body clearance reduced in mild to moderate hepatic and renal impairment
- Pediatric safety demonstrated in ages 6 months to 5 years
- Clearance reduced in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in dry place away from light and heat
- Keep out of the reach of children