Rinobas 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ebastine |
| Company | Jenphar bangladesh ltd |
Indications
- Seasonal and Perennial Allergic Rhinitis
- Chronic Idiopathic Urticaria
Pharmacology
Ebastine is a long-acting and selective H1-histamine receptor antagonist. After repeated administration, inhibition of peripheral receptors remains at a constant level. Ebastine is rapidly absorbed and undergoes extensive first-pass metabolism following oral administration. Ebastine is almost totally converted to the pharmacologically active acid metabolite, carebastine.
Dosage & Administration
- Tablet: Adults (more than 12 years of age): 10 mg (one tablet) once daily. Children (6-12 years of age): 5 mg (half tablet) once daily.
- Syrup:
- Children (2-5 years of age): 2.5 ml once daily (upto 5 ml in severe cases such as Perennial Allergic Rhinitis)
- Children (6-12 years of age): 5 ml once daily (upto 10 ml in severe cases such as Perennial Allergic Rhinitis)
- Additional Info: Ebastine may be taken with or without food.
Interaction
Rinobas in combination with ketoconazole or erythromycin increases plasma level of Rinobas and prolonged QTc interval. Rinobas does not interact with the pharmacokinetics of theophylline, warfarin, cimetidine, diazepam, or alcohol. The sedation effect of alcohol and diazepam may be enhanced.
Contraindications
Patients with a known hypersensitivity to Ebastine or any of its ingredients.
Side Effects
- Headache
- Dry Mouth
- Drowsiness
- Abdominal Pain
- Dyspepsia
- Nausea
- Insomnia
Overdose Effects
No clinically meaningful signs or symptoms were observed up to 100 mg given once daily. There is no specific antidote for Rinobas. In case of accidental overdoses, gastric lavage, monitoring of vital functions including ECG and symptomatic treatment should be carried out.
Therapeutic Class
Non-sedating antihistamines
Storage Conditions
Store below 30°C at a cool and dry place, away from light. Keep out of reach of children