Tebast 10 mg (Tablet)
Unit Price: ৳ 6.02 (3 x 10: ৳ 180.60)
Strip Price: ৳ 60.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Ebastine |
| Company | Square pharmaceuticals plc |
Indications
- Seasonal and Perennial Allergic Rhinitis
- Chronic Idiopathic Urticaria
Pharmacology
- Ebastine is a long-acting and selective H1-histamine receptor antagonist
- Inhibition of peripheral receptors remains at a constant level after repeated administration
- Rapid absorption and extensive first-pass metabolism following oral administration
- Almost total conversion to the pharmacologically active acid metabolite, carebastine
Dosage & Administration
- Tablet dosage for adults (more than 12 years of age): 10 mg once daily
- Tablet dosage for children (6-12 years of age): 5 mg once daily
- Syrup dosage for children (2-5 years of age): 2.5 ml once daily (up to 5 ml in severe cases such as Perennial Allergic Rhinitis)
- Syrup dosage for children (6-12 years of age): 5 ml once daily (up to 10 ml in severe cases such as Perennial Allergic Rhinitis)
- Ebastine may be taken with or without food
Interaction
- Increased plasma level of Tebast and prolonged QTc interval when combined with ketoconazole or erythromycin
- No interaction with the pharmacokinetics of theophylline, warfarin, cimetidine, diazepam, or alcohol
- Enhanced sedation effect of alcohol and diazepam
Contraindications
- Known hypersensitivity to Ebastine or any of its ingredients
Side Effects
- Common side effects: headache, dry mouth, drowsiness
- Less common side effects: abdominal pain, dyspepsia, nausea, insomnia
Overdose Effects
- No clinically meaningful signs or symptoms observed up to 100 mg given once daily
- No specific antidote for Tebast
- In case of accidental overdoses: gastric lavage, monitoring of vital functions including ECG, and symptomatic treatment
Therapeutic Class
- Non-sedating antihistamines
Storage Conditions
- Store below 30°C at a cool and dry place, away from light
- Keep out of reach of children