Ebahist 5 mg/5 ml (Syrup)
50 ml bottle: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ebastine |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Seasonal and Perennial Allergic Rhinitis
- Chronic Idiopathic Urticaria
Pharmacology
- Ebastine is a long-acting and selective H1-histamine receptor antagonist
- After repeated administration, inhibition of peripheral receptors remains at a constant level
- Ebastine is rapidly absorbed and undergoes extensive first-pass metabolism following oral administration
- Ebastine is almost totally converted to the pharmacologically active acid metabolite, carebastine
Dosage & Administration
- Adults (more than 12 years of age): 10 mg (one tablet) once daily
- Children (6-12 years of age): 5 mg (half tablet) once daily
- Children (2-5 years of age): 2.5 ml once daily (up to 5 ml in severe cases such as Perennial Allergic Rhinitis)
- Ebastine may be taken with or without food
Interaction
- Ebahist in combination with either ketoconazole or erythromycin increases in plasma level of Ebahist and prolonged QTc interval
- Ebahist does not interact with the pharmacokinetics of theophylline, warfarin, cimetidine, diazepam or alcohol
- The sedation effect of alcohol and diazepam may be enhanced
Contraindications
- Patients with a known hypersensitivity to Ebastine or any of its ingredients
Side Effects
- Headache
- Dry mouth
- Drowsiness
- Abdominal pain
- Dyspepsia
- Nausea
- Insomnia
Overdose Effects
- No clinically meaningful signs or symptoms were observed up to 100 mg given once daily
- There is no specific antidote for Ebahist
- In case of accidental overdoses, gastric lavage, monitoring of vital functions including ECG and symptomatic treatment should be carried out
Therapeutic Class
- Non-sedating antihistamines
Storage Conditions
- Store below 30°C at a cool and dry place, away from light
- Keep out of reach of children