Ebasten 10 mg (Tablet)

Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Ebastine
Company Aci limited
Also available as

Indications

  • Seasonal and Perennial Allergic Rhinitis
  • Chronic Idiopathic Urticaria

Pharmacology

  • Ebastine is a long-acting and selective H1-histamine receptor antagonist
  • Inhibition of peripheral receptors remains at a constant level after repeated administration
  • Ebastine is rapidly absorbed and undergoes extensive first-pass metabolism
  • Almost totally converted to the pharmacologically active acid metabolite, carebastine

Dosage & Administration

  • Tablet: Adults (more than 12 years of age): 10 mg (one tablet) once daily
  • Tablet: Children (6-12 years of age): 5 mg (half tablet) once daily
  • Syrup: Children (2-5 years of age): 2.5 ml once daily (up to 5 ml in severe cases)
  • Syrup: Children (6-12 years of age): 5 ml once daily (up to 10 ml in severe cases)
  • Ebastine may be taken with or without food

Interaction

  • Combination with ketoconazole or erythromycin increases plasma level and prolonged QTc interval
  • No interaction with the pharmacokinetics of theophylline, warfarin, cimetidine, diazepam, or alcohol
  • Enhanced sedation effect of alcohol and diazepam

Contraindications

  • Known hypersensitivity to Ebastine or any of its ingredients

Side Effects

  • Common side-effects: headache, dry mouth, drowsiness
  • Less commonly reported side effects: abdominal pain, dyspepsia, nausea, insomnia

Overdose Effects

  • No clinically meaningful signs or symptoms observed up to 100 mg given once daily
  • No specific antidote for Ebasten
  • In case of accidental overdose: gastric lavage, monitoring of vital functions including ECG, and symptomatic treatment

Therapeutic Class

  • Non-sedating antihistamines

Storage Conditions

  • Store below 30°C at a cool and dry place, away from light
  • Keep out of reach of children

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