Liptor 20 mg (Tablet)

Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00

Medicine Details

Title

  • Liptor 20 mg Tablet

Categories

  • Cholesterol-lowering medication
  • Cardiovascular medication
  • Statins

Indications

  • Reduction of total cholesterol and LDL cholesterol
  • Treatment of hypertriglyceridemia
  • Prevention of cardiovascular events

Mode of Action

  • Selective inhibitor of HMG-CoA reductase
  • Lowers plasma cholesterol and lipoprotein levels
  • Increases hepatic LDL receptors for enhanced uptake of LDL

Absorption

Rapidly absorbed after oral administration; maximum plasma concentrations occur within 1 to 2 hours

Distribution

  • Mean volume of distribution is approximately 381 liters
  • 98% bound to plasma proteins

Metabolism

  • Extensively metabolized to ortho- and parahydroxylated derivatives
  • In vitro studies suggest importance of metabolism by cytochrome P450 3A4

Excretion

  • Eliminated primarily in bile
  • Mean plasma elimination half-life is approximately 14 hours in humans

Dosage & Administration

  • Initial dose of 10 mg once daily for adults
  • Dosage can be increased at intervals of at least 4 weeks based on response
  • Dosage range of 10 to 80 mg once daily
  • Can be administered as a single dose at any time of the day, with or without food

Interactions

  • Increased risk of myopathy with concurrent administration of certain drugs
  • Plasma concentrations affected by coadministration with antacid, colestipol, digoxin, erythromycin, oral contraceptives, and warfarin

Contraindications

  • Hypersensitivity to any component of the medication
  • Active liver disease or unexplained persistent elevations of serum transaminases
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

Side Effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Not known whether excreted in human milk
  • Potential for serious adverse reactions in breastfeeding women

Precautions & Warnings

  • Liver function tests should be performed before initiation of treatment and periodically thereafter
  • Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected

Use in Special Populations

  • Higher plasma concentrations in healthy elderly subjects
  • No clinically significant difference in LDL-C reduction between men and women
  • No influence on plasma concentrations or LDL-C reduction in renal insufficiency
  • Markedly increased plasma concentrations in patients with chronic alcoholic liver disease

Overdose Effects

Specific treatment not available; patient should be treated symptomatically and supportive measures instituted, as required

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

Keep in a dry place away from light and heat; keep out of the reach of children

Chemical Structure

  • Molecular Formula: C33H35FN2O5

Commonly Asked Questions about Liptor 20 mg Tablet

  • What is Liptor 20 mg Tablet?
  • How should I take Liptor 20 mg Tablet?
  • What are the uses of Liptor 20 mg Tablet?
  • What are the Side Effects of Liptor 20 mg Tablet?
  • What are the instructions for storage and disposal of Liptor 20 mg Tablet?
  • Is Liptor 20 mg Tablet used for lowering cholesterol?
  • Will taking Liptor 20 mg Tablet increase my risk of diabetes?
  • For how long do I need to take Liptor 20 mg Tablet? Is it safe for long-term use?
  • Does Liptor 20 mg Tablet cause weight loss?
  • Can I stop taking Liptor 20 mg Tablet?
  • Does Liptor 20 mg Tablet cause memory loss?
  • Does Liptor 20 mg Tablet make you tired?
  • Can Liptor 20 mg Tablet be prescribed to children?
  • Is Liptor 20 mg Tablet a blood thinner?

Quick Tips

  • Liptor 20 mg Tablet is generally safe
  • May cause diarrhea, gas, or upset stomach - take with food if these occur
  • Inform your doctor if you experience fatigue, muscle weakness, or muscle pain
  • Liver function should be checked before and during treatment
  • Not to be used during pregnancy, planning a pregnancy, or breastfeeding

Other Information

This medication is a prescription drug and should be used as directed by a healthcare professional

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