Alanil 120 mg (Tablet)

Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00

Medicine Details

Title

  • Alanil 120 mg Tablet

Categories

  • Medicines
  • Health & Beauty

Indications

  • Relief of symptoms associated with seasonal and perennial allergic rhinitis
  • Relief of symptoms associated with chronic idiopathic urticaria

Pharmacology

  • Fexofenadine is considered an 'inverse agonist' of the H1 receptor
  • Potent and selective affinity for H1 receptors
  • No evidence of antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
  • Does not cross the blood-brain barrier

Dosage & Administration

  • Adults and children 12 years and older: 60 mg twice daily or 120 mg once daily or 180 mg once daily
  • In case of impaired renal function: 60 mg once daily
  • Children from 6 to 11 years: 30 mg twice daily or 60 mg once daily

Interaction

  • Coadministration with erythromycin or ketoconazole results in a 2-3 times increase in the level of fexofenadine in plasma
  • No interaction between fexofenadine and omeprazole observed
  • Administration of antacids containing aluminium and magnesium hydroxide gels 15 minutes prior to Alanil causes a reduction in bioavailability

Contraindications

  • Known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients

Side Effects

  • Common: headache, drowsiness, dizziness, nausea
  • Uncommon: fatigue
  • Frequency with which other undesirable effects occur is not known
  • Immune system disorders: hypersensitivity reactions, angioedema, chest tightness, dyspnoea, flushing, systemic anaphylaxis

Pregnancy & Lactation

  • No adequate data from the use of Fexofenadine hydrochloride in pregnant women
  • Fexofenadine hydrochloride should not be used during pregnancy unless clearly necessary
  • Fexofenadine hydrochloride is not recommended for mothers breast-feeding their babies
  • No human data on the effect of Fexofenadine hydrochloride on fertility available

Precautions & Warnings

  • Limited data in older people and renally or hepatically impaired patients
  • Administered with care in these special groups
  • Patients with a history of or ongoing cardiovascular disease should be warned about potential adverse reactions

Use in Special Populations

  • Renal impairment: dose of 60 mg once daily recommended as the starting dose
  • Moderate to severe hepatic disease does not substantially affect the pharmacokinetics of fexofenadine
  • Elderly patients: pharmacokinetics of fexofenadine is altered, increased bioavailability

Overdose Effects

  • Dizziness, drowsiness, fatigue, dry mouth reported with overdose
  • No development of clinically significant adverse reactions with doses administered to healthy subjects
  • Symptomatic and supportive treatment recommended
  • Haemodialysis does not effectively remove Alanil from blood

Therapeutic Class

  • Non-sedating antihistamines

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C32H39NO4

Common Questions

  • Works by blocking histamine during an allergic reaction
  • Relieves symptoms of allergic rhinitis and urticaria
  • Side effects include vomiting, headache, coughing, diarrhea, hives, and swelling
  • Should be kept in a cool dry place and in its original pack

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