Alfex 120 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Title

  • Alfex 120 mg Tablet

Categories

  • Medicine
  • Antihistamine

Description

  • Alfex is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis and chronic idiopathic urticaria. It improves health-related quality of life and work/activity productivity.

Dosage

  • Adults and children 12 years and older: Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily.

Age

  • Adults
  • Children 2-11 years
  • Children 6-11 years
  • Children 6 months to less than 2 years
  • Patients over 65 years of age

Symptoms

  • Sneezing
  • Rhinorrhea
  • Lacrimation
  • Itchy, red eyes
  • Itchy nose/palate/throat
  • Pruritus
  • Number of wheals
  • Angioedema
  • Chest tightness
  • Dyspnoea
  • Flushing
  • Systemic anaphylaxis
  • Insomnia
  • Nervousness
  • Tachycardia
  • Palpitations
  • Diarrhea
  • Rash
  • Urticaria
  • Hypersensitivity reactions with manifestations

Adverse Effects

  • Headache
  • Drowsiness
  • Dizziness
  • Nausea
  • Fatigue
  • Vomiting
  • Coughing
  • Painful menstruation
  • Pain in the arms and legs
  • Hives and redness of skin
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Dry mouth

Administration

  • Oral administration
  • Twice daily administration
  • Once daily administration
  • In case of impaired renal function: adjusted dosage

Interactions

  • No clinically significant interaction with omeprazole
  • Increased level when coadministered with erythromycin or ketoconazole
  • Reduction in bioavailability with antacids

Contraindications

  • Known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients

Pregnancy and Lactation

  • Not recommended for use during pregnancy or breastfeeding

Storage

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C32H39NO4

Pharmacology

  • Fexofenadine is considered an 'inverse agonist' of the H1 receptor
  • Potent and selective affinity for H1 receptors

Therapeutic Class

  • Non-sedating antihistamines

Renal Function

  • Altered pharmacokinetics in individuals with renal impairment
  • Dose adjustment required

Hepatic Function

  • No substantial effect on the pharmacokinetics of fexofenadine in moderate to severe hepatic disease

Overdose Effects

  • Dizziness
  • Drowsiness
  • Fatigue
  • Symptomatic and supportive treatment recommended

Precautions

  • Limited data in older people and renally or hepatically impaired patients
  • Careful administration in patients with ongoing cardiovascular disease

Usability

  • No significant effects on central nervous system function
  • Unlikely to affect the ability to drive or use machines

Allergy Relief

  • Relieves symptoms of sneezing, rhinorrhea, lacrimation, itchy, red eyes, itchy nose/palate/throat
  • Reduces signs and symptoms of chronic idiopathic urticaria

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