Axodin 180 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fexofenadine hydrochloride |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Title
- Axodin 180 mg Tablet
Categories
- Antihistamines
- Allergic Rhinitis Relief
- Urticaria Treatment
Indications
- Relief of symptoms associated with seasonal and perennial allergic rhinitis
- Relief of symptoms associated with chronic idiopathic urticaria
- Improvement of health-related quality of life and work/activity productivity
Pharmacology
- H1 histamine receptor mediation
- Degranulation of mast cells and basophils
- Release of histamine and inflammatory mediators
- Fexofenadine as an inverse agonist of the H1 receptor
- Selective affinity for H1 receptors
- No evidence of antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
- Does not cross the blood-brain barrier
Dosage & Administration
- Adult dosage: 60 mg twice daily or 120 mg once daily or 180 mg once daily
- Children 6-11 years: 30 mg twice daily or 60 mg once daily
- Children 2-11 years: 30 mg or 5 ml suspension twice daily
- Nocturnal dosing recommended for renal impairment
- Dosage adjusted for impaired renal function
- Dosage related to age and severity of condition
Interaction
- Potential interaction with erythromycin or ketoconazole
- Increased plasma level with coadministration of specific medicinal products
- No interaction with omeprazole
- Reduction in bioavailability with antacids
- Recommended 2-hour interval between Axodin and antacids
Contraindications
- Hypersensitivity to Fexofenadine Hydrochloride or its ingredients
Side Effects
- Nervous system disorders: headache, drowsiness, dizziness
- Gastrointestinal disorders: nausea
- Immune system disorders: hypersensitivity reactions
- Psychiatric disorders: insomnia, nervousness, sleep disorders
- Cardiac disorders: tachycardia, palpitations
- Skin and subcutaneous tissue disorders: rash, urticaria, pruritus
- Frequency-based reporting of undesirable effects
Pregnancy & Lactation
- Limited data on use in pregnant women
- No data on human milk content
- Not recommended during breastfeeding
- No human data on effect on fertility
- No harmful effects indicated in limited animal studies
Precautions & Warnings
- Limited data in elderly and impaired patients
- Special care in cardiovascular disease history
- Unlikely to affect ability to drive or operate machinery
- Recommendation to check individual response before driving or performing tasks
Use in Special Populations
- Altered pharmacokinetics in renal impairment and elderly patients
- Dosing recommendations for renal and hepatic impaired patients
Overdose Effects
- Reported effects of dizziness, drowsiness, fatigue, and dry mouth
- No clinically significant adverse reactions at specific doses
- Standard measures and symptomatic treatment recommended
Therapeutic Class
- Non-sedating antihistamines
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C32H39NO4
- Chemical Structure Image
Common Questions about Axodin 180 mg Tablet
- Description of medication as an antihistamine
- Uses in the treatment of allergic rhinitis and urticaria
- Reported side effects
- Instructions for storage and disposal
- Potential for causing sleepiness
- Onset and duration of action
- Effectiveness for outdoor and indoor allergies
- Guidance for coping with dizziness
- Caution against antacid combination
- Guidelines for medication intake
- Recommendations for dietary restrictions
- Caution for patients with heart problems
- Quick tips for medication usage