Dinafex 180 mg (Tablet)
Unit Price: ৳ 10.00 (4 x 10: ৳ 400.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fexofenadine hydrochloride |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal allergic rhinitis
- Relief of symptoms associated with perennial allergic rhinitis
- Relief of symptoms associated with chronic idiopathic urticaria
- Improves health-related quality of life
- Improves work/activity productivity
Pharmacology
- Responsible for mediating hypersensitivity and allergic reactions
- Binds to and activates H1 receptors
- Results in the release of pro-inflammatory cytokines
- Prevents activation of H1 receptors
- Potent and selective affinity for H1 receptors
- Does not cross the blood-brain barrier
Dosage & Administration
- Adult dosage: 60 mg twice daily or 120 mg once daily or 180 mg once daily
- Children 6 to 11 years dosage: 30 mg twice daily or 60 mg once daily
- Children 2 to 11 years suspension dosage: 30 mg or 5 ml twice daily
- Dosage adjustments for impaired renal function
Interaction
- No hepatic biotransformation
- Increased level with erythromycin or ketoconazole
- No interaction with omeprazole
- Reduction in bioavailability with aluminium and magnesium hydroxide containing antacids
Contraindications
- Known hypersensitivity to Fexofenadine Hydrochloride
Side Effects
- Headache
- Drowsiness
- Nausea
- Fatigue
- Hypersensitivity reactions
- Insomnia
- Tachycardia
- Diarrhea
- Rash
- Pruritus
Pregnancy & Lactation
- No adequate data in pregnant women
- Limited animal studies show no harmful effects
- Not recommended for breastfeeding mothers
- No human data on fertility
Precautions & Warnings
- Limited data in older people and renally or hepatically impaired patients
- Administered with care in special groups
- Warning for patients with ongoing cardiovascular disease
- Unlikely to produce significant effects on the ability to drive or use machines
Use in Special Populations
- Altered pharmacokinetics in renal impairment
- No substantial effect on pharmacokinetics of fexofenadine in hepatic disease
- Adverse events similar in elderly patients
- Increased bioavailability in individuals over 65 years
Overdose Effects
- Dizziness
- Drowsiness
- Fatigue
- Dry mouth
- No clinically significant adverse reactions reported
Therapeutic Class
- Non-sedating antihistamines
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C32H39NO4
Common Questions about Dinafex 180 mg Tablet
- Blocks histamine during allergic reactions
- Used for treatment of allergic rhinitis and urticaria
- Reported side effects include vomiting, headache, coughing, diarrhea
- Storage and disposal instructions
- Potential to cause sleepiness
- Starts working within 1 hour of consumption
- Relieves symptoms of outdoor and indoor allergies
- Coping with dizziness
- Avoiding antacids while taking the tablet
- Impact on heart problems
- Quick tips for usage