Fenadin 30 mg/5 ml (Oral Suspension)

30 ml bottle: ৳ 35.00

Medicine Details

Indications

  • Relief of symptoms associated with seasonal allergic rhinitis in adults and children 12 years of age and over
  • Relief of symptoms associated with perennial allergic rhinitis in adults and children 12 years of age and over
  • Relief of symptoms associated with chronic idiopathic urticaria in adults and children 12 years of age and older
  • Improves health-related quality of life
  • Improves work/activity productivity

Pharmacology

  • H1 histamine receptor mediation
  • Inhibition of degranulation of mast cells and basophils
  • Blockage of histamine release and other inflammatory mediators
  • Prevention of activation and downstream effects of H1 receptors
  • Potent and selective affinity for H1 receptors
  • No evidence of carrying antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
  • Does not cross the blood-brain barrier

Dosage & Administration

  • 60 mg tablet dosage for adults and children 12 years and older
  • 120 mg tablet dosage for adults and children 12 years and older
  • 180 mg tablet dosage for adults and children 12 years and older
  • 30 mg tablet dosage for children from 6 to 11 years
  • 30 mg or 5 ml suspension dosage for children from 2 to 11 years
  • 15 mg or 2.5 ml suspension dosage for children from 6 months to less than 2 years
  • Recommended starting dose of 60 mg once daily for patients with decreased renal function

Interaction

  • No hepatic biotransformation
  • Coadministration with erythromycin or ketoconazole may increase fexofenadine level in plasma
  • No interaction observed between fexofenadine and omeprazole
  • Reduction in bioavailability when coadministered with antacids containing aluminium and magnesium hydroxide
  • Advisable to leave 2 hours between administration of fexofenadine and antacids

Contraindications

  • Known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients

Side Effects

  • Headache
  • Drowsiness
  • Dizziness
  • Nausea
  • Fatigue
  • Hypersensitivity reactions
  • Insomnia
  • Tachycardia
  • Palpitations
  • Diarrhea
  • Rash
  • Urticaria
  • Pruritus

Pregnancy & Lactation

  • No adequate data in pregnant women
  • No direct or indirect harmful effects indicated in limited animal studies
  • Not recommended for breastfeeding mothers

Precautions & Warnings

  • Administration with care in older people and renally or hepatically impaired patients
  • Patients with history of or ongoing cardiovascular disease should be warned
  • Unlikely to produce significant effects on the ability to drive or use machines

Use in Special Populations

  • Altered pharmacokinetics in individuals with renal impairment
  • No substantial effect on pharmacokinetics in individuals with moderate to severe hepatic disease
  • Adverse events similar in elderly patients compared to patients under 65 years of age

Overdose Effects

  • Dizziness
  • Drowsiness
  • Fatigue
  • Dry mouth
  • Maximum tolerated dose not established
  • Standard measures for removal of unabsorbed medicinal product
  • Symptomatic and supportive treatment recommended
  • Haemodialysis does not effectively remove fexofenadine from blood

Therapeutic Class

  • Non-sedating antihistamines

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C32H39NO4

Common Questions about Fenadin 30 mg/5 ml Suspension

  • Relief of allergy symptoms such as runny nose, itching eyes/nose, sneezing, hives, and itching
  • Reported side effects including vomiting, headache, coughing, diarrhea, painful menstruation, pain in the arms and legs, hives, redness of skin, swelling of face, lips, eyelids, tongue, hands and feet
  • Instructions for storage and disposal
  • Medication can cause sleepiness
  • Onset of action within 1 hour
  • Benefit observed within 6 hours
  • Relief of symptoms of outdoor and indoor allergies
  • Coping strategies for dizziness
  • Interaction with antacids
  • Dosing recommendations
  • Avoidance of certain foods or drinks
  • Caution for patients with heart problems
  • Quick tips for medication use

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