Fexo 30 mg/5 ml (Oral Suspension)
50 ml bottle: ৳ 55.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fexofenadine hydrochloride |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Relief of symptoms associated with seasonal and perennial allergic rhinitis
- Relief of symptoms associated with chronic idiopathic urticaria
- Improvement of health-related quality of life
- Improvement of work/activity productivity
Pharmacology
- Role of H1 histamine receptor in mediating hypersensitivity and allergic reactions
- Degranulation of mast cells and basophils
- Release of histamine and other inflammatory mediators
- Binding and activation of H1 receptors by histamine
- Downstream effects of histamine binding on allergic symptoms
- Fexofenadine as an 'inverse agonist' of the H1 receptor
- Potent and selective affinity of fexofenadine for H1 receptors
- Lack of cross of fexofenadine over the blood-brain barrier
Dosage & Administration
- Recommended dosage for adults and children 12 years and older
- Options for dosage based on age and renal function
- Dosage for children from 6 months to less than 2 years for chronic idiopathic urticaria
- Modification of dosage in cases of impaired renal function
Interaction
- Non-hepatic biotransformation of fexofenadine
- Potential interaction with erythromycin or ketoconazole
- Impact of coadministration with omeprazole
- Effect of antacids containing aluminium and magnesium hydroxide on bioavailability
Contraindications
- Known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients
Side Effects
- Reported undesirable effects in clinical trials
- Incidence of undesirable effects in post-marketing surveillance
- Specific undesirable effects related to nervous system, gastrointestinal system, general conditions, immune system, psychiatric disorders, cardiac disorders, and skin and subcutaneous tissue disorders
Pregnancy & Lactation
- Limited data from the use of Fexofenadine hydrochloride in pregnant women
- Limited evidence of direct or indirect harmful effects on pregnancy, embryonal/foetal development, parturition, or postnatal development based on animal studies
- Recommendation against use during pregnancy unless clearly necessary
- Potential exposure of Fexofenadine in human milk
- Recommendation against use by mothers breastfeeding their babies
- Lack of human data on the effect of Fexofenadine hydrochloride on fertility
Precautions & Warnings
- Limited data in older people and renally or hepatically impaired patients
- Careful administration in special groups
- Warning for patients with a history of or ongoing cardiovascular disease
- Impact on ability to drive and use machines
- Pharmacodynamic profile and reported adverse reactions
Use in Special Populations
- Altered pharmacokinetics in individuals with renal impairment
- Recommendation for starting dose in patients with decreased renal function
- Limited impact of moderate to severe hepatic disease on the pharmacokinetics of fexofenadine
- Similar adverse events in elderly patients compared to patients under 65 years of age
- Alteration in the pharmacokinetics of fexofenadine in individuals over 65 years of age
Overdose Effects
- Reported effects of dizziness, drowsiness, fatigue, and dry mouth
- Administration of single doses up to 800 mg without clinically significant adverse reactions
- Lack of establishment of the maximum tolerated dose of Fexo
- Recommendation for standard measures and symptomatic and supportive treatment
Therapeutic Class
- Classification as non-sedating antihistamines
Storage Conditions
- Requirement to keep in a dry place away from light and heat
- Necessity to keep out of the reach of children
Chemical Structure
- Molecular Formula: C32H39NO4
- Visual representation of the chemical structure of Fexofenadine Hydrochloride
Common Questions about Fexo 30 mg/5 ml Suspension
- Explanation of Fexo 30 mg/5 ml Suspension as an antihistamine
- Uses of Fexo 30 mg/5 ml Suspension for allergic rhinitis and urticaria
- Reported side effects of Fexo 30 mg/5 ml Suspension
- Instructions for storage and disposal of Fexo 30 mg/5 ml Suspension
- Potential of Fexo 30 mg/5 ml Suspension to cause sleepiness
- Recommendation against overdosing on Fexo 30 mg/5 ml Suspension
- Onset of action and peak benefit of Fexo 30 mg/5 ml Suspension
- Relief of symptoms caused by outdoor and indoor allergies by Fexo 30 mg/5 ml Suspension
- Guidance on coping with dizziness due to Fexo 30 mg/5 ml Suspension
- Precautions in combination of Fexo 30 mg/5 ml Suspension with antacids
- Directions for taking Fexo 30 mg/5 ml Suspension based on doctor's recommendation
- Advice to avoid specific food or drink while taking Fexo 30 mg/5 ml Suspension
- Caution for individuals with heart problems when using Fexo 30 mg/5 ml Suspension
- Quick Tips related to the nature and usage of Fexo 30 mg/5 ml Suspension