Liplo 10 mg (Tablet)
Unit Price: ৳ 3.33 (3 x 30: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet for reducing cholesterol levels
- Treatment for familial hypercholesterolemia
- Reduction of triglycerides levels
- Prevention of cardiac ischaemic events
- Treatment for dysbetalipoproteinaemia
- Usable for patients with coronary artery disease
- Recommended for patients with diabetes mellitus
- Designed for patients with renal transplantation
Pharmacology
- Selective inhibitor of HMG-CoA reductase
- Lowers plasma cholesterol levels
- Increases hepatic LDL receptors
- Rapid oral absorption
- Extensive metabolism by cytochrome P450 3A4
- Primarily eliminated in bile
- Long plasma elimination half-life
Dosage & Administration
- Initial adult dose: 10 mg once daily
- Maximum dose: 80 mg once daily
- Initial child dose: 10 mg once daily
- Usual child max dose: 20 mg once daily
- Adjustable dosage based on response
Interactions
- Increased myopathy risk with certain drugs
- Altered plasma concentrations with antacid
- Enhanced LDL-C reduction with colestipol
- Possible interaction with digoxin
- Increased plasma concentrations with erythromycin
- Affects oral contraceptives and warfarin
- No significant effect on prothrombin time
Contraindications
- Hypersensitivity to any component
- Active liver disease
- Unexplained elevated transaminases
- History of serious adverse reactions
Side Effects
- Well-tolerated with minor side effects
- Common side effects: constipation, flatulence
- Other side effects: infection, headache
- Potential side effects: rash, myalgia
Pregnancy & Lactation
- Contraindicated during pregnancy
- Safety not established in pregnant women
- Potential risk of congenital anomalies
- Not recommended during breastfeeding
Precautions & Warnings
- Liver function tests recommended before treatment
- Caution in patients with alcohol consumption
- Discontinue if elevated CPK levels occur
- Close monitoring for myopathy
Use in Special Populations
- Higher plasma concentrations in elderly
- No significant difference between genders
- No dose adjustment for renal dysfunction
- Markedly increased plasma concentrations in liver disease
Overdose Effects
- No specific treatment available
- Symptomatic and supportive care recommended
- Liver function and CK levels monitoring advised
- Hemodialysis unlikely to enhance clearance
Therapeutic Class
- Belongs to Other Anti-anginal & Anti-ischaemic drugs
- Categorized under Statins
Storage Conditions
- Store in dry place away from light and heat
- Keep out of reach of children
Chemical Structure
- Molecular formula: C33H35FN2O5
- Chemical structure provided
Common Questions about Liplo 10 mg Tablet
- Definition and uses of Liplo 10 mg Tablet
- Instructions for administration
- List of side effects
- Guidelines for storage and disposal
- Relation to diabetes risk and memory loss
- Recommendation not to stop medication abruptly