Fexofen 120 mg (Tablet)
Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fexofenadine hydrochloride |
| Company | Somatec pharmaceuticals ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal and perennial allergic rhinitis
- Relief of symptoms associated with chronic idiopathic urticaria
Pharmacology
- Responsible for mediating hypersensitivity and allergic reactions
- Binds to and activates H1 receptors, causing release of pro-inflammatory cytokines
- Potent and selective affinity for H1 receptors
- Does not cross the blood-brain barrier
Dosage & Administration
- 60 mg to 180 mg once or twice daily for adults and children 12 years and older
- 30 mg to 60 mg once or twice daily for children 6 to 11 years
- 30 mg or 5 ml twice daily for children 2 to 11 years
- 15 mg or 2.5 ml to 30 mg or 5 ml for children with impaired renal function
Interaction
- Does not undergo hepatic biotransformation
- Coadministration with erythromycin or ketoconazole results in increased plasma levels
- No interaction with omeprazole
- Antacid administration 15 minutes prior causes reduction in bioavailability
Contraindications
- Known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients
Side Effects
- Nervous system disorders like headache, drowsiness, and dizziness
- Gastrointestinal disorders like nausea
- Immune system disorders like hypersensitivity reactions
- Cardiac disorders like tachycardia and palpitations
- Skin and subcutaneous tissue disorders like rash, urticaria, and pruritus
Pregnancy & Lactation
- Limited data in pregnant women
- Fexofenadine found in human breast milk
- Not recommended for breastfeeding mothers
- No human data on effect on fertility
Precautions & Warnings
- Limited data in older people and renally or hepatically impaired patients
- Patients with ongoing cardiovascular disease should be warned about adverse reactions
- Unlikely to produce effect on ability to drive or use machines
Use in Special Populations
- Alterations in pharmacokinetics in individuals with renal impairment
- Moderate to severe hepatic disease does not substantially affect pharmacokinetics
- Adverse events were similar in elderly patients
Overdose Effects
- Reported effects of dizziness, drowsiness, fatigue, and dry mouth
- No development of clinically significant adverse reactions at administered doses
- Symptomatic and supportive treatment recommended
Therapeutic Class
- Non-sedating antihistamines
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C32H39NO4
- Chemical Structure: (Refer to provided image)
Common Questions about Fexofen 120 mg Tablet
- Works by blocking histamine during allergic reaction
- Used for allergic rhinitis and urticaria
- Reported side effects include vomiting, headache, coughing, and more
- Instructions for storage and disposal
- Can cause sleepiness and should not be overdosed
- Starts working within 1 hour and peaks in 6 hours
- Relieves symptoms of outdoor and indoor allergies
- Caution with dizziness, use in combination with antacids, and avoiding certain juices
- Effects on ability to drive or use machines
- Do not consume specific juices while taking Fexofen 120 mg Tablet
- Caution for heart disorders
- Quick Tips for usage