Fexofen 30 mg/5 ml (Oral Suspension)
50 ml bottle: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fexofenadine hydrochloride |
| Company | Somatec pharmaceuticals ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal allergic rhinitis
- Relief of symptoms associated with perennial allergic rhinitis
- Relief of symptoms associated with chronic idiopathic urticaria
Pharmacology
- H1 histamine receptor mediation of hypersensitivity and allergic reactions
- Degranulation of mast cells and basophils
- Release of histamine and inflammatory mediators
- Binding of histamine to H1 receptors
- Stabilization of the inactive form of the H1 receptor by fexofenadine
- Lack of evidence of antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
- No significant CNS effects due to lack of crossing the blood-brain barrier
Dosage & Administration
- Recommended dosage for adults and children 12 years and older
- Different dosage for impaired renal function
- Tablet options: 60 mg, 120 mg, 180 mg
- Suspension options: 30 mg or 5 ml, 15 mg or 2.5 ml, 30 mg or 5 ml (1 tsp)
Interaction
- No hepatic biotransformation
- Increased level of fexofenadine with coadministration of erythromycin or ketoconazole
- No interaction between fexofenadine and omeprazole
- Reduction in bioavailability with antacids containing aluminium and magnesium hydroxide
Contraindications
- Known hypersensitivity to fexofenadine hydrochloride or its ingredients
Side Effects
- Frequency ratings for undesirable effects
- Reported undesirable effects in adults in clinical trials
- Reported undesirable effects in post-marketing surveillance
- Hypersensitivity reactions, insomnia, tachycardia, diarrhea, rash
Pregnancy & Lactation
- Limited data on use in pregnant women
- No data on human milk content
- Not recommended for breastfeeding mothers
- No human data on effect on fertility
Precautions & Warnings
- Limited data in older people and renally or hepatically impaired patients
- Use with care in special groups
- Warning for patients with history of or ongoing cardiovascular disease
- Unlikely effect on ability to drive or use machines
Use in Special Populations
- Altered pharmacokinetics in individuals with renal impairment
- No substantial impact on pharmacokinetics in moderate to severe hepatic disease
- Similar adverse events in elderly patients
- Altered pharmacokinetics in individuals over 65 years of age
Overdose Effects
- Reported effects of overdose: dizziness, drowsiness, fatigue, dry mouth
- No clinically significant adverse reactions at specific doses
- Recommendation for symptomatic and supportive treatment
Therapeutic Class
- Non-sedating antihistamines
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C32H39NO4
- Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-468-fexofenadine-hydrochloride-chemical-structure-HrM3XW8ofnGVhLdcBRox.svg
Common Questions about Fexofen 30 mg/5 ml Suspension
- Definition of Fexofen 30 mg/5 ml Suspension
- Uses of Fexofen 30 mg/5 ml Suspension
- Side effects of Fexofen 30 mg/5 ml Suspension
- Instructions for storage and disposal of Fexofen 30 mg/5 ml Suspension
- Potential sleepiness caused by Fexofen 30 mg/5 ml Suspension
- Risk of overdose on Fexofen 30 mg/5 ml Suspension
- Onset of action of Fexofen 30 mg/5 ml Suspension
- Relief of symptoms by Fexofen 30 mg/5 ml Suspension
- Coping with dizziness caused by Fexofen 30 mg/5 ml Suspension
- Interaction between antacids and Fexofen 30 mg/5 ml Suspension
- Proper administration of Fexofen 30 mg/5 ml Suspension
- Avoidance of specific food or drink while taking Fexofen 30 mg/5 ml Suspension
- Risk of heart problems with Fexofen 30 mg/5 ml Suspension
- Quick Tips for using Fexofen 30 mg/5 ml Suspension