Fixal 60 mg (Tablet)

Unit Price: ৳ 5.02 (3 x 10: ৳ 150.60)
Strip Price: ৳ 50.20

Medicine Details

Title

  • Fixal 60 mg Tablet

Category

  • Medicine
  • Healthcare
  • Pharmaceutical

Indications

  • Relief of symptoms associated with seasonal and perennial allergic rhinitis
  • Relief of symptoms associated with chronic idiopathic urticaria

Pharmacology

  • Fexofenadine as an inverse agonist of the H1 receptor
  • Selective affinity for H1 receptors
  • No evidence of antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity

Dosage & Administration

  • Adult dosage: 60mg twice daily or 120mg/180mg once daily
  • Children dosage: 30mg/60mg twice daily or 30mg once daily
  • Special dosage for impaired renal function

Interaction

  • No hepatic biotransformation
  • Potential interaction with erythromycin or ketoconazole
  • No interaction with omeprazole
  • Impact of antacids containing aluminium and magnesium hydroxide on bioavailability

Contraindications

  • Known hypersensitivity to Fexofenadine Hydrochloride or its ingredients

Side Effects

  • Nervous system disorders: headache, drowsiness, dizziness
  • Gastrointestinal disorders: nausea
  • Immune system disorders: hypersensitivity reactions
  • Cardiac disorders: tachycardia, palpitations
  • Skin and subcutaneous tissue disorders: rash, urticaria, pruritus

Pregnancy & Lactation

  • Limited data on the use in pregnant women
  • Potential cross into human breast milk
  • Not recommended for mothers breastfeeding their babies

Precautions & Warnings

  • Limited data in older people and renally or hepatically impaired patients
  • Care for patients with a history of or ongoing cardiovascular disease
  • Unlikely to produce an effect on the ability to drive or use machines
  • Individual response check before driving or performing complicated tasks

Use in Special Populations

  • Altered pharmacokinetics in individuals with renal impairment
  • Moderate to severe hepatic disease does not substantially affect pharmacokinetics
  • Adverse events similarity in elderly patients compared to patients under 65 years of age
  • Altered pharmacokinetics in individuals over 65 years of age

Overdose Effects

  • Reported effects: dizziness, drowsiness, fatigue, dry mouth
  • No clinically significant adverse reactions at certain doses
  • Recommendation for symptomatic and supportive treatment

Therapeutic Class

  • Non-sedating antihistamines

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C32H39NO4
  • Chemical Structure Image

Common Questions about Fixal 60 mg Tablet

  • Description of Fixal 60 mg Tablet as an antihistamine
  • Uses of Fixal 60 mg Tablet for allergic rhinitis and urticaria
  • List of reported side effects of Fixal 60 mg Tablet
  • Instructions for storage and disposal
  • Potential sleepiness as a side effect
  • Time to start working and relief of symptoms
  • Ability to relieve symptoms of outdoor and indoor allergies
  • Guidance for coping with dizziness and avoiding certain foods or drinks

Max Tolerated Dose

  • Maximum tolerated dose not established

Interactions with Antacids

  • Decreased absorption of Fixal 60 mg Tablet when used in combination with antacids

Effect of Fixal on Ability to Drive

  • Unlikely to produce an effect on the ability to drive or use machines

Impact on Fertility

  • No human data on the effect of Fexofenadine hydrochloride on fertility are available
  • No effect on fertility in mice with fexofenadine hydrochloride treatment

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