Fixal 180 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fexofenadine hydrochloride |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Relief of symptoms associated with allergic rhinitis
- Relief of symptoms associated with chronic idiopathic urticaria
Pharmacology
- H1 histamine receptor mediation
- Mechanism of action of fexofenadine
Dosage & Administration
- Adult dosage for allergic rhinitis
- Child dosage for chronic idiopathic urticaria
Interaction
- Interactions with erythromycin and ketoconazole
- No interaction with omeprazole observed
Contraindications
- Known hypersensitivity to Fexofenadine Hydrochloride
Side Effects
- Common side effects in adults
- Post-marketing surveillance reported side effects
Pregnancy & Lactation
- Limited data in pregnant women
- Not recommended for breastfeeding mothers
Precautions & Warnings
- Limited data in elderly and impaired patients
- Warnings for patients with cardiovascular disease
Use in Special Populations
- Pharmacokinetics in renal and hepatic impaired patients
- Effects on elderly patients
Overdose Effects
- Reported effects of overdose
- Maximum tolerated dose not established
Therapeutic Class
- Non-sedating antihistamines
Storage Conditions
- Storage instructions to keep product dry and away from light and heat
Chemical Structure
- Molecular Formula: C32H39NO4
- Chemical structure image provided
Common Questions about Fixal 180 mg Tablet
- Information on uses, side effects, storage, and more
Dosage Forms
- Tablet
- Suspension
Age Group
- Adults
- Children 6 to 11 years
- Children 2 to 11 years
- Children 6 months to less than 2 years
Medication Frequency
- Twice daily
- Once daily
Route of Administration
- Oral
Renal Function Consideration
- Impaired renal function dosages
Special Precautions
- Special care in elderly and renally/hepatically impaired patients
- Warnings for patients with cardiovascular history
Absorption Factors
- Interaction with antacids causing reduced bioavailability
Adverse Reaction Monitoring
- Common reported side effects in clinical trials
- Post-marketing surveillance for additional side effects
Symptom Improvement
- Relief of symptoms such as sneezing, itching, rhinorrhea
- Improvement in health-related quality of life
Mechanism of Action
- Inverse agonist activity on H1 receptor
- Selective affinity for H1 receptors
Bioavailability
- Altered bioavailability in renal impairment
- Increased bioavailability in elderly patients
Storage Instructions
- Keep in original pack
- Keep out of reach of children and pets
Chemical Components
- Fexofenadine Hydrochloride
Frequency of Use
- As required
- Regular dosing schedules
Biochemical Effects
- Stabilization of inactive form of H1 receptor
Activity Productivity
- Improvement in work/activity productivity
Immunological Effects
- Reduction in allergic symptoms
- Significantly reduces signs and symptoms of chronic idiopathic urticaria
Severe Side Effects
- Hypersensitivity reactions
- Cardiac disorders like tachycardia and palpitations
Impaired Renal Function
- Dosage adjustments for impaired renal function
Effects on Fertility
- No human data on fertility effects
- No effect on fertility observed in mice
Dosage Adjustment
- Adjustments based on renal function
- Starting dose recommendations
Contraindicated Population
- Patients with known hypersensitivity
Critical Interaction
- Coadministration with erythromycin or ketoconazole
Enhanced Absorption
- Alternative dosing for impaired renal function
- Efficient absorption in moderate to severe hepatic disease
Avoidance Instructions
- Avoid antacids prior to administration
- Avoid interaction with aluminium and magnesium hydroxide-containing antacids
Monitoring Recommendations
- Monitoring for adverse reactions
- Individual response assessment before activities like driving
Effects on Central Nervous System
- Unlikely to cause significant CNS effects
- No sedative effects reported
Adverse Reactions
- Reporting of side effects in decreasing seriousness
- Frequency-based classification of side effects
Special Population Considerations
- Pharmacokinetic alterations in elderly patients
- Starting doses for individuals with decreased renal function
Unwanted Effects
- Nervous system disorders
- General disorders and administration site conditions
Maternal Health
- Limited data on impact during pregnancy
- Precautions for pregnant women
Breastfeeding Precautions
- Not recommended for breastfeeding mothers
- Crossing into human breast milk observed
Pediatric Dosage Forms
- Suspension dosage for children
- Tablet dosage for children and adults
Medication Schedule
- Twice daily dosing
- Once daily dosing
Dietary Restrictions
- Avoid intake with fruit juices
- Avoid specific food/drinks to ensure effectiveness
Cardiovascular Warning
- Patients with heart problems should use caution
- Alternative medication for individuals with heart disorders
Central Nervous System Tolerance
- Negative effects unlikely on driving abilities
- No significant effects on CNS function reported
Biochemical Stabilization
- Stabilization of H1 receptors by fexofenadine
- Prevention of downstream effects of histamine binding
Hepatic Biotransformation
- Absence of hepatic biotransformation interactions
- Limited impact on medicinal product interactions
Dosage Schedule
- Multiple dosing options for different age groups
- Impaired renal function consideration in dosing
Allergic Symptom Relief
- Relief of symptoms like sneezing, itching eyes/nose/throat
- Symptom improvement in seasonal and perennial allergic rhinitis
Compatibility Information
- No interaction with omeprazole observed
- Interaction with antacids causing reduced bioavailability