Lozin 5 mg (Tablet)
Unit Price: ৳ 3.01 (100's pack: ৳ 301.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Levocetirizine dihydrochloride |
| Company | Kemiko pharmaceuticals ltd |
Indications
- perennial allergic rhinitis
- seasonal allergic rhinitis
- chronic idiopathic urticaria
Pharmacology
- Contains Levocetirizine Dihydrochloride
- Levocetirizine is the active (Levo) isomer of cetirizine
- Highly effective and well-tolerated nonsedating antihistamine
- Has potent antiallergic properties
- Two-fold higher affinity for H1 receptors than cetirizine
- Rapid and long-acting action
- Allows once-a-day administration
Dosage & Administration
- Adult and children 12 years of age and older: 5 mg once daily
- Children 6 to 11 years of age: 2.5 mg (½ tablet or 1 teaspoon oral solution) once daily
- Children 6 months to 5 years of age: 1.25 mg (½ teaspoon oral solution) once daily
- Pediatric use: Based on extrapolation of efficacy from adults
- Geriatric use: Insufficient data for patients aged 65 years and older
- Hepatic impairment: No dosage adjustment required
- Renal impairment:
- Mild (creatinine clearance: 50-80 ml/min): 2.5 mg once daily
- Moderate (creatinine clearance: 30-50 ml/min): 2.5 mg once every other day
- Severe (creatinine clearance: 10-30 ml/min): 2.5 mg twice weekly (administered once every 3-4 days)
- End-stage renal disease patients and patients undergoing hemodialysis: should not receive Levocetirizine
Interaction
Not known to have any interactions with other drugs
Contraindications
- Hypersensitivity to levocetirizine, cetirizine or its parent compound hydroxyzine
- Severe renal impairment (creatinine clearance: <10 ml/min)
Side Effects
- Well tolerated
- Rarely reported side effects: headache, dry mouth, fatigue, skin rash
Pregnancy & Lactation
- Pregnancy Category B
- Use during pregnancy only if clearly needed
- Excreted in breast milk, not recommended for nursing mothers
Precautions & Warnings
- Epileptic patients and patients at risk of convulsions
- Renal impairment
- Pregnancy and lactation
Overdose Effects
No clinically relevant adverse events reported in case of overdose
Therapeutic Class
Non-sedating antihistamines
Storage Conditions
Store at a temperature not exceeding 30°C in a dry place. Protect from light