Megatrol 5 mg (Tablet)

Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)

Medicine Details

Indications

  • Perennial allergic rhinitis
  • Seasonal allergic rhinitis
  • Chronic idiopathic urticaria

Pharmacology

  • Contains Levocetirizine Dihydrochloride
  • Levocetirizine is the active (Levo) isomer of cetirizine
  • Highly effective and well-tolerated nonsedating antihistamine
  • Potent antiallergic properties
  • Two-fold higher affinity for H1 receptors than cetirizine
  • Rapid and long-acting action
  • Once-a-day administration

Dosage & Administration

  • Recommended dose for adults and children 12 years and older: 5 mg once daily
  • Recommended dose for children 6 to 11 years of age: 2.5 mg once daily
  • Recommended dose for children 6 months to 5 years of age: 1.25 mg once daily
  • Pediatric use based on extrapolation of efficacy from adults
  • Geriatric use not sufficiently studied
  • No dosage adjustment for patients with solely hepatic impairment
  • Renal impairment dosage recommendations based on creatinine clearance levels

Interaction

  • Not known to have any interactions with other drugs

Contraindications

  • Hypersensitivity to levocetirizine, cetirizine, or hydroxyzine
  • Severe renal impairment (creatinine clearance: <10 ml/min)

Side Effects

  • Well tolerated, with rare reports of headache, dry mouth, fatigue, and skin rash

Pregnancy & Lactation

  • Pregnancy Category B
  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy only if clearly needed
  • Excreted in breast milk, not recommended for nursing mothers

Precautions & Warnings

  • Epileptic patients and patients at risk of convulsions
  • Renal impairment
  • Pregnancy and lactation

Overdose Effects

  • No clinically relevant adverse events reported in case of overdose
  • Symptomatic and supportive treatment recommended in the event of overdosage

Therapeutic Class

  • Non-sedating antihistamines

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Store in a dry place
  • Protect from light

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