Aleze 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 30.00

Medicine Details

Category Details
Generic Loratadine
Company Unimed unihealth pharmaceuticals ltd
Also available as

Indications

  • Fast relief from seasonal allergic rhinitis
  • Relief from perennial allergic rhinitis
  • Alleviation of skin allergies
  • Effective for chronic urticaria
  • Relieves symptoms of sneezing
  • Relieves nasal discharge
  • Provides relief from itching
  • Effective for ocular itching and burning

Pharmacology

  • Preparation of Loratadine
  • Non-sedative histamine H1 receptor antagonist
  • Long-acting tricyclic antihistamine
  • Selective peripheral H1-receptor antagonistic activity
  • Rapidly effective and long-lasting
  • Allows once-a-day administration

Dosage & Administration

  • Adult dosage: One tablet daily
  • Morning administration recommended
  • Children dosage based on body weight
  • Safety and efficacy not established for children under 2 years

Interaction

  • No reports of potentially hazardous interactions with other drugs
  • No potentiating effects with alcohol
  • Concomitant therapy caution with hepatic cytochromes P450 3A4 and 2D6
  • Cimetidine inhibits both enzymes
  • Erythromycin or ketoconazole inhibits P450 3A4

Contraindications

  • Contraindicated in patients with hypersensitivity or idiosyncrasy to components

Side Effects

  • Comparable adverse event incidence to placebo
  • Comparable to placebo in driving performance and cognitive functioning

Pregnancy & Lactation

  • Not advisable during human pregnancy
  • Excreted in breast milk in a very small amount
  • Nursing mothers advised not to take the drug

Precautions & Warnings

  • Caution in patients with liver impairment or renal insufficiency (eGFR <30 ml/min)

Overdose Effects

  • Reported effects in adults and children with overdose
  • Symptomatic and supportive measures recommended for overdosage
  • Prompt instituting and maintenance of measures necessary
  • Consideration of oral activated charcoal for large overdoses

Therapeutic Class

  • Non-sedating antihistamines

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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