Orva 10 mg (Tablet)

Unit Price: ৳ 12.04 (2 x 15: ৳ 361.20)
Strip Price: ৳ 180.60

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Synovia pharma plc
Also available as
Orva 20 mg tablet

Title

  • Orva 10 mg Tablet

Categories

  • Cholesterol-lowering medication
  • Cardiovascular medication
  • Lipid-lowering agents
  • Pharmacotherapy

Description

  • Orva 10 mg Tablet is used to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B) and triglycerides levels in patients with certain diseases when response to diet and other non-pharmacological measures is inadequate.

Dimensions

  • N/A

Color Options

  • N/A

Functions

  • Reduces total cholesterol and LDL cholesterol
  • Lowers apolipoprotein B (Apo-B) levels
  • Decreases triglycerides levels
  • Reduces cardiac ischaemic events
  • Adjunct to diet for specific conditions

Materials

  • Atorvastatin

Technical Specifications

  • Selectively inhibits HMG-CoA reductase
  • Lowers plasma cholesterol and lipoprotein levels
  • Increases hepatic LDL receptors
  • Rapidly absorbed after oral administration

Design Elements

  • Chemical Structure: C33H35FN2O5

Usability Features

  • Once daily dosage
  • Can be taken with or without food
  • Plasma concentrations are higher in elderly subjects
  • No gender-based difference in LDL-C reduction
  • No clinically significant influence on plasma concentrations in renal insufficiency
  • Markedly increased plasma concentrations in chronic alcoholic liver disease

Indications

  • Reduces elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B) and triglycerides levels in specific diseases
  • Used for familial hypercholesterolaemia, mixed dyslipidemia, hypertriglyceridaemia, dysbetalipoproteinaemia, and coronary artery disease with elevated LDL-cholesterol level

Pharmacology

  • Selective inhibitor of HMG-CoA reductase
  • Lowers plasma cholesterol and lipoprotein levels
  • Enhances uptake and catabolism of LDL
  • Rapidly absorbed after oral administration
  • Metabolized to ortho- and parahydroxylated derivatives
  • Eliminated primarily in bile

Dosage & Administration

  • Adult dosage range: 10-80 mg once daily
  • Initial 10 mg dose for children (10-18 years)
  • Dose adjustments based on lipid levels
  • Analysis of lipid levels within 2 to 4 weeks after initiation

Interaction

  • Increased risk of myopathy with concurrent administration of certain drugs
  • Plasma concentrations affected when coadministered with antacid, colestipol, digoxin, erythromycin, oral contraceptives
  • No clinically significant effect on prothrombin time when administered to patients receiving chronic warfarin treatment

Contraindications

  • Hypersensitivity to any component of this medication
  • Active liver disease or unexplained persistent elevations of serum transaminases
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

Side Effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • No established safety in pregnant women
  • Animal studies show toxicity to reproduction
  • Not recommended during breastfeeding

Precautions & Warnings

  • Liver function tests should be performed before initiation of treatment and periodically thereafter
  • Caution in patients who consume alcohol or have a history of liver disease
  • Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected

Use in Special Populations

  • Plasma concentrations higher in elderly subjects
  • No clinically significant difference in LDL-C reduction between men and women
  • No influence on plasma concentrations or LDL-C reduction in renal insufficiency
  • Markedly increased plasma concentrations in chronic alcoholic liver disease

Overdose Effects

  • Specific treatment not available
  • Symptomatic treatment
  • Liver function tests and serum CK levels monitoring
  • Hemodialysis not expected to significantly enhance clearance

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C33H35FN2O5

Common Questions

  • What is Orva 10 mg Tablet?
  • How should I take Orva 10 mg Tablet?
  • What are the uses of Orva 10 mg Tablet?
  • What are the Side Effects of Orva 10 mg Tablet?
  • What are the instructions for storage and disposal Orva 10 mg Tablet?
  • Is Orva 10 mg Tablet used for lowering cholesterol?
  • Will taking Orva 10 mg Tablet increase my risk of diabetes?
  • For how long do I need to take Orva 10 mg Tablet? Is it safe for long-term use?
  • Does Orva 10 mg Tablet cause weight loss?
  • Can I stop taking Orva 10 mg Tablet?
  • Does Orva 10 mg Tablet cause memory loss?
  • Does Orva 10 mg Tablet make you tired?
  • Can Orva 10 mg Tablet be prescribed to children?
  • Is Orva 10 mg Tablet a blood thinner?
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