Rupafen 10 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Indications

  • Seasonal Allergic Rhinitis
  • Perennial Allergic Rhinitis
  • Urticaria

Pharmacology

  • Long-acting
  • Non-sedative antagonist of histamine H1-receptors
  • Antagonizes platelet activating factor (PAF)
  • Dual mode of action
  • Inhibition of degranulation of mast cells
  • Inhibition of release of cytokines

Dosage & Administration

  • Recommended dose for Adults and adolescents: 10 mg once a day
  • Recommended dose for Children aged 2 to 11 years
  • Can be taken with or without food

Interaction

  • Concomitant administration with ketoconazole or erythromycin increases systemic exposure
  • Caution with statins, CNS depressants, or alcohol
  • Not to be taken with grapefruit or grapefruit juice

Contraindications

  • Hypersensitivity to Rupatadine or excipients

Side Effects

  • Common: Asthenia, dizziness, drowsiness
  • Uncommon: Appetite increased, arthralgia, back pain
  • Rare: Palpitations, tachycardia

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Not recommended during lactation unless benefits outweigh risks

Precautions & Warnings

  • Use with caution in patients with known prolongation of the QT interval
  • Use with caution in elderly patients
  • Not recommended in patients with impaired kidney or liver function

Use in Special Populations

  • Caution in elderly
  • Safety and efficacy not established in patients less than 12 years of age
  • Not recommended in patients with renal or hepatic insufficiency

Overdose Effects

  • Most common adverse reaction: Somnolence
  • Symptomatic treatment required for accidental ingestion of very high doses

Therapeutic Class

  • Non-sedating antihistamines

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C26H26ClN3
  • Chemical Structure image available

Common Questions about Rupafen 10 mg Tablet

  • H1-receptors antagonist
  • Used for allergic rhinitis and urticaria
  • Unsafe to use during pregnancy
  • Unknown effect during breastfeeding
  • Caution with driving and kidney function
  • No clinical experience in patients with impaired kidney or liver function
  • Onset of action in the first 75 minutes
  • Duration of action is 8 to 10 hrs
  • Quick tips provided by doctor

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