Rupatrol 10 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rupatadine fumarate |
| Company | Square pharmaceuticals plc |
Indications
- Symptomatic treatment of Seasonal Allergic Rhinitis
- Symptomatic treatment of Perennial Allergic Rhinitis
- Symptomatic treatment of Urticaria
Pharmacology
- Long-acting non-sedative antagonist of histamine H1-receptors
- Antagonist of platelet activating factor (PAF)
- Inhibition of degranulation of mast cells
- Inhibition of release of cytokines
- Better therapeutic effect than isolated antihistamine
Dosage & Administration
- Recommended dose for adults and adolescents: 10 mg once a day
- Dosage for children aged 2 to 11 years based on weight
Interaction
- Increased systemic exposure when administered concomitantly with ketoconazole or erythromycin
- Caution required when co-administered with statins, CNS depressants, or alcohol
- Avoid concomitant use with grapefruit and grapefruit juice
Contraindications
- Hypersensitivity to Rupatadine or any of the excipients
Side Effects
- Common: Asthenia, dizziness, drowsiness
- Uncommon: Appetite increased, arthralgia, back pain, concentration impaired
- Rare: Palpitations, tachycardia
Pregnancy & Lactation
- No clinical data available on use during pregnancy
- Not recommended during lactation unless potential benefits justify the potential risk to the infant
Precautions & Warnings
- Use with caution in patients with known prolongation of QT interval
- Caution in elderly patients (65 years and older)
- Not recommended in patients with impaired kidney or liver function
Use in Special Populations
- Caution advised in elderly patients
- Safety and efficacy not established in patients less than 12 years of age
- Not recommended in patients with renal or hepatic insufficiency
Overdose Effects
- Most common adverse reaction: somnolence
- Symptomatic treatment and required supportive measures in case of accidental ingestion of high doses
Therapeutic Class
- Non-sedating antihistamines
Storage Conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C26H26ClN3
Common Questions
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