G-Lidocaine 2% (Injection)

Indications

• Local anaesthetic for infiltration blockade and intravenous regional analgesia
• Prevention and treatment of ventricular tachyarrhythmias

Description

• Sterile, non-pyrogenic, aqueous solution
• Contains G-G-Lidocaine
• Amide type local anaesthetic
• Fast onset and intermediate duration of action

Pharmacology

• Inhibits sodium influx through sodium specific ion channels
• Acts on voltage-gated sodium channels
• State dependent blockade

Dosage

• Adjusted according to patient's response and site of administration
• Maximum individual dose for healthy adults
• Recommended doses for infiltration, peripheral nerve blocks, sympathetic nerve blocks, central neural blocks, etc.

Administration

• Intravenous dose for antiarrhythmic treatment
• Technique for antiarrhythmic treatment
• Loading dose for achieving steady state

Interactions

• Cimetidine can impair metabolism of lidocaine
• Significant increases in plasma lidocaine concentrations with beta blockers
• Prolongs duration of action of suxamethonium

Contraindications

• Known hypersensitivity to anaesthetics of the amide type

Side Effects

• Rare adverse reactions
• Systemic effects involving CNS and cardiovascular system
• Excitatory and depressant CNS reactions
• Cardiovascular reactions
• Allergic reactions

Pregnancy & Lactation

• Caution during early pregnancy
• Caution when administered to nursing women

Precautions & Warnings

• Should be employed by clinicians well versed in diagnosis and management of dose-related toxicity
• Dependence on proper dosage, correct technique, and readiness for emergencies
• Consulting standard text books for specific techniques and precautions
• Availability of resuscitative equipment and drugs
• Caution in patients with epilepsy, impaired cardiac conduction, impaired respiratory function, impaired hepatic function

Use in Special Populations

• Dosage reduction in children
• Elderly patients may be more sensitive

Therapeutic Class

• Local & Surface anesthesia

Storage Conditions

• Keep below 25°C temperature
• Away from light & moisture
• Keep out of the reach of children

Related Brands

• Lidocaine 2% (Injection) - medimet-pharmaceuticals-ltd