Nebazin (5 mg+500 IU)/gm (Ointment)
20 gm tube: ৳ 43.90
Medicine Details
Category | Details |
---|---|
Generic | Neomycin sulfate bacitracin zinc |
Company | Incepta pharmaceuticals ltd |
Indications
- Treatment of topical bacterial infections
- Effective in atopic, contact stasis and infections
- Useful in eczematoid dermatitis, neurodermatitis, eczema, anogenital pruritus
- Adjunct in certain pyodermas such as impetigo
Pharmacology
- Bacitracin inhibits bacterial cell wall synthesis
- Active against gram-positive bacteria
- Neomycin binds to bacterial ribosome, inhibiting protein synthesis
- Active against gram negative aerobes including some strains of staphylococci
Dosage & Administration
- Ointment application: two to three times daily
- Dusting powder application: up to 4 times daily
Interaction
- Increased risk of nephrotoxicity with other nephrotoxic drugs
- May enhance the action of neuromuscular-blocking agents
- Additive nephrotoxic and neurotoxic effect with other aminoglycosides and specific drugs
- Enhanced toxicity with potent diuretics
- May impair the absorption of other drugs
- May enhance the effect of acarbose and non-depolarising muscle relaxants
- May antagonize the parasympathomimetic effect of neostigmine and pyridostigmine
Contraindications
- Hypersensitivity to any of its components
Side Effects
- Usually well tolerated
- Rare cases of allergic reactions
Pregnancy & Lactation
- Use during pregnancy only if potential benefit justifies the potential risk to the fetus
Precautions & Warnings
- Avoid use on large open wounds or severely injured skin, or areas exuding large volumes of fluid
- Avoid use for otitis externa when the eardrum is perforated
- Consult physician for deep or puncture wounds, animal bites, or serious burns
- Discontinue use and consult physician if condition persists or worsens in minor skin injuries
- Not recommended for use in neonates
Use in Special Populations
- Suitable for use in children at the same dose as adults
- Dose should be reduced in infants
- Not recommended for use in neonates
Therapeutic Class
- Ophthalmic and Topical antibacterial products
Storage Conditions
- Store in a cool and dry place, protected from light
- Keep out of reach of children
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