Neobacin (5 mg+500 IU)/gm (Ointment)
20 gm tube: ৳ 44.03
Medicine Details
Category | Details |
---|---|
Generic | Neomycin sulfate bacitracin zinc |
Company | Kemiko pharmaceuticals ltd |
Indications
- Treatment of topical bacterial infections
- Effective in atopic, contact stasis and infections, eczematoid dermatitis, neurodermatitis, eczema, anogenital pruritus
- Adjunct in pyodermas such as impetigo
- Effective during specific systemic antibiotic therapy
Pharmacology
- Bacitracin inhibits bacterial cell wall synthesis
- Active against gram-positive bacteria
- Neomycin binds to bacterial ribosome
- Inhibits protein synthesis
- Active against gram negative aerobes
- Active against some strains of staphylococci
Dosage & Administration
- Ointment for affected skin area
- Clean area before application
- Apply two to three times daily
- Dusting Powder for superficial skin infections
- Apply up to 4 times daily
Interaction
- Increased risk of nephrotoxicity with other nephrotoxic drugs
- May enhance the action of neuromuscular-blocking agents
- Additive nephrotoxic and neurotoxic effect with other aminoglycosides
- May impair the absorption of other drugs
- May enhance the effect of acarbose
- May alter INR when given with anticoagulants
Contraindications
- Hypersensitivity to any of its components
Side Effects
- Usually well-tolerated
- Rare allergic reactions
Pregnancy & Lactation
- Safe use during pregnancy & lactation not established
- Use during pregnancy if benefit justifies potential risk to fetus
Precautions & Warnings
- Should not be used on large open wounds or severely injured skin
- Not recommended for the treatment of otitis external when eardrum is perforated
- Consult physician for deep wounds, animal bites, or serious burns
- Discontinue if condition persists or worsens
- Not recommended for longer than 1 week without physician's direction
Use in Special Populations
- Suitable for use in children at adult dose, but reduced in infants
- Not recommended for use in neonates
Therapeutic Class
- Ophthalmic and Topical antibacterial products
Storage Conditions
- Keep out of reach of children
- Store in a cool and dry place
- Protected from light
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