Neobacin (5 mg+500 IU)/gm (Ointment)

20 gm tube: ৳ 44.03

Medicine Details

Category Details
Generic Neomycin sulfate bacitracin zinc
Company Kemiko pharmaceuticals ltd

Indications

  • Treatment of topical bacterial infections
  • Effective in atopic, contact stasis and infections, eczematoid dermatitis, neurodermatitis, eczema, anogenital pruritus
  • Adjunct in pyodermas such as impetigo
  • Effective during specific systemic antibiotic therapy

Pharmacology

  • Bacitracin inhibits bacterial cell wall synthesis
  • Active against gram-positive bacteria
  • Neomycin binds to bacterial ribosome
  • Inhibits protein synthesis
  • Active against gram negative aerobes
  • Active against some strains of staphylococci

Dosage & Administration

  • Ointment for affected skin area
  • Clean area before application
  • Apply two to three times daily
  • Dusting Powder for superficial skin infections
  • Apply up to 4 times daily

Interaction

  • Increased risk of nephrotoxicity with other nephrotoxic drugs
  • May enhance the action of neuromuscular-blocking agents
  • Additive nephrotoxic and neurotoxic effect with other aminoglycosides
  • May impair the absorption of other drugs
  • May enhance the effect of acarbose
  • May alter INR when given with anticoagulants

Contraindications

  • Hypersensitivity to any of its components

Side Effects

  • Usually well-tolerated
  • Rare allergic reactions

Pregnancy & Lactation

  • Safe use during pregnancy & lactation not established
  • Use during pregnancy if benefit justifies potential risk to fetus

Precautions & Warnings

  • Should not be used on large open wounds or severely injured skin
  • Not recommended for the treatment of otitis external when eardrum is perforated
  • Consult physician for deep wounds, animal bites, or serious burns
  • Discontinue if condition persists or worsens
  • Not recommended for longer than 1 week without physician's direction

Use in Special Populations

  • Suitable for use in children at adult dose, but reduced in infants
  • Not recommended for use in neonates

Therapeutic Class

  • Ophthalmic and Topical antibacterial products

Storage Conditions

  • Keep out of reach of children
  • Store in a cool and dry place
  • Protected from light

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