Taven 20 mg (Tablet)
Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | Renata limited |
| Also available as |
Title
- Taven 20 mg Tablet
Categories
- Cholesterol-lowering medication
- Statins
- Anti-anginal drug
- Anti-ischaemic drug
Description
- Indicated for reducing elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B), and triglycerides levels in various diseases
- Selective inhibitor of HMG-CoA reductase
- Rapidly absorbed after oral administration with maximum plasma concentrations within 1-2 hours
- Approximately 98% bound to plasma proteins
- Extensively metabolized to ortho- and parahydroxylated derivatives
- Primarily eliminated in bile following hepatic and/or extra-hepatic metabolism
- Recommended starting dose is 10 or 20 mg once daily, with a dosage range of 10 to 80 mg once daily
- Interacts with drugs like cyclosporine, fibric acid derivatives, niacin, erythromycin, azole antifungals, antacids, colestipol, digoxin, oral contraceptives, and warfarin
- Contraindicated in patients with hypersensitivity to any component, active liver disease, unexplained persistent elevations of serum transaminases, and history of serious adverse reaction
- Common side effects include constipation, flatulence, dyspepsia, abdominal pain, infection, headache, back pain, rash, asthenia, arthralgia, and myalgia
- Not recommended during pregnancy or lactation
- Liver function tests should be performed before the initiation of treatment and periodically thereafter
- Higher plasma concentrations observed in elderly subjects compared to young adults
- No clinically significant difference in LDL-C reduction between men and women
- No dose adjustment necessary in patients with renal dysfunction
- Specific treatment not available for overdose, with supportive measures instituted as required
- Belongs to the therapeutic class of Other Anti-anginal & Anti-ischaemic drugs, Statins
- Should be stored in a dry place away from light and heat, and out of the reach of children
Dimensions
Color options
Functions
- Selective inhibitor of HMG-CoA reductase
- Reduces total cholesterol and LDL cholesterol
- Lowers apolipoprotein B (Apo-B) and triglycerides levels
- Increases the number of hepatic LDL receptors for enhanced uptake and catabolism of LDL
- Rapidly absorbed after oral administration
- Extensively metabolized to ortho- and parahydroxylated derivatives
- Primarily eliminated in bile following hepatic and/or extra-hepatic metabolism
Materials
Technical specifications
- Maximum plasma concentrations occur within 1 to 2 hours
- Absolute bioavailability of approximately 14%
- Systemic availability of HMG-CoA reductase inhibitory activity of approximately 30%
- Mean volume of distribution of approximately 381 liters
- Mean plasma elimination half-life of approximately 14 hours
Design elements
Usability features
- Can be taken with or without food
- Plasma concentrations are higher in healthy elderly subjects compared to young adults
- No dose adjustment necessary in patients with renal dysfunction
- Supportive measures instituted as required for overdose
- Belongs to the therapeutic class of Other Anti-anginal & Anti-ischaemic drugs, Statins
- Should be stored in a dry place away from light and heat, and out of the reach of children
Other
- Risk of myopathy increased with concurrent administration of specific drugs
- Interacts with multiple drugs including antacids, colestipol, digoxin, and erythromycin
- Not recommended during pregnancy or lactation
- Liver function tests should be performed before the initiation of treatment and periodically thereafter
- Higher plasma concentrations observed in elderly subjects compared to young adults
- Specific treatment not available for overdose, with supportive measures instituted as required