Neocin (5 mg+250 IU)/gm (Topical Powder)

5 gm pack: ৳ 15.47 (5's pack: ৳ 77.35)

Medicine Details

Category Details
Generic Neomycin sulfate bacitracin zinc
Company Opsonin pharma ltd
Also available as
Neocin 5 mg ointment

Indications

  • Treatment of topical bacterial infections
  • Effective in atopic, contact stasis, and infections
  • Useful in eczematoid dermatitis, neurodermatitis, eczema, anogenital pruritus
  • Adjunct in certain pyodermas such as impetigo

Pharmacology

  • Bacitracin inhibits bacterial cell wall synthesis
  • Active against many gram-positive bacteria and some gram-negative species
  • Neomycin binds to the 30S subunits of the bacterial ribosome
  • Inhibits protein synthesis and disrupts DNA synthesis

Dosage & Administration

  • Ointment: apply two to three times daily to the affected skin area
  • Dusting Powder: apply a light dusting of the powder up to 4 times daily

Interaction

  • Bacitracin Zinc: increased risk of nephrotoxicity when used with other nephrotoxic drugs
  • Neomycin Sulphate: additive nephrotoxic and neurotoxic effect with other aminoglycosides
  • May enhance the action of neuromuscular-blocking agents

Contraindications

  • Hypersensitivity to any of its components

Side Effects

  • Well tolerated, rare cases of allergic reactions

Pregnancy & Lactation

  • Safe use during pregnancy & lactation not established
  • Use during pregnancy only if potential benefit justifies potential risk to the fetus

Precautions & Warnings

  • Avoid using on large open wounds or severely injured skin
  • Not recommended for use on perforated eardrums due to risk of ototoxicity
  • Consult a physician for deep wounds, animal bites, or serious burns
  • Discontinue use and consult physician if condition persists or worsens

Use in Special Populations

  • Suitable for use in children at the same dose as adults, but the dose should be reduced in infants
  • Not recommended for use in neonates

Therapeutic Class

  • Ophthalmic and Topical antibacterial products

Storage Conditions

  • Keep all medicines out of reach of children
  • Store in a cool and dry place, protected from light

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