Neocin (5 mg+250 IU)/gm (Topical Powder)
5 gm pack: ৳ 15.47 (5's pack: ৳ 77.35)
Medicine Details
Category | Details |
---|---|
Generic | Neomycin sulfate bacitracin zinc |
Company | Opsonin pharma ltd |
Also available as |
Indications
- Treatment of topical bacterial infections
- Effective in atopic, contact stasis, and infections
- Useful in eczematoid dermatitis, neurodermatitis, eczema, anogenital pruritus
- Adjunct in certain pyodermas such as impetigo
Pharmacology
- Bacitracin inhibits bacterial cell wall synthesis
- Active against many gram-positive bacteria and some gram-negative species
- Neomycin binds to the 30S subunits of the bacterial ribosome
- Inhibits protein synthesis and disrupts DNA synthesis
Dosage & Administration
- Ointment: apply two to three times daily to the affected skin area
- Dusting Powder: apply a light dusting of the powder up to 4 times daily
Interaction
- Bacitracin Zinc: increased risk of nephrotoxicity when used with other nephrotoxic drugs
- Neomycin Sulphate: additive nephrotoxic and neurotoxic effect with other aminoglycosides
- May enhance the action of neuromuscular-blocking agents
Contraindications
- Hypersensitivity to any of its components
Side Effects
- Well tolerated, rare cases of allergic reactions
Pregnancy & Lactation
- Safe use during pregnancy & lactation not established
- Use during pregnancy only if potential benefit justifies potential risk to the fetus
Precautions & Warnings
- Avoid using on large open wounds or severely injured skin
- Not recommended for use on perforated eardrums due to risk of ototoxicity
- Consult a physician for deep wounds, animal bites, or serious burns
- Discontinue use and consult physician if condition persists or worsens
Use in Special Populations
- Suitable for use in children at the same dose as adults, but the dose should be reduced in infants
- Not recommended for use in neonates
Therapeutic Class
- Ophthalmic and Topical antibacterial products
Storage Conditions
- Keep all medicines out of reach of children
- Store in a cool and dry place, protected from light
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