Neocitrin (5 mg+250 IU)/gm (Topical Powder)

10 gm pack: ৳ 20.14

Medicine Details

Category Details
Generic Neomycin sulfate bacitracin zinc
Company Aci limited

Indications

  • Treatment of topical bacterial infections
  • Effective in atopic, contact stasis and infections, eczematoid dermatitis, neurodermatitis, eczema, anogenital pruritus
  • Useful as an adjunct in certain pyodermas, such as impetigo
  • Specific systemic antibiotic therapy for infections

Pharmacology

  • Bacitracin inhibits bacterial cell wall synthesis
  • Active against many gram-positive and some gram-negative bacteria
  • Neomycin binds to the bacterial ribosome, inhibiting protein synthesis
  • Active against many gram-negative aerobes and some strains of staphylococci

Dosage & Administration

  • Ointment: Apply two to three times daily to the affected skin area
  • Dusting Powder: Apply to the affected skin area up to 4 times daily

Interaction

  • Bacitracin Zinc: Increased risk of nephrotoxicity when used with other nephrotoxic drugs
  • Neomycin Sulphate: Additive nephrotoxic and neurotoxic effect with other aminoglycosides
  • May impair the absorption of other drugs
  • May enhance the effect of non-depolarising muscle relaxants

Contraindications

  • Hypersensitivity to any of its components

Side Effects

  • Well tolerated, allergic reactions in rare cases

Pregnancy & Lactation

  • Safe use not established during pregnancy & lactation
  • Use during pregnancy only if the potential benefit justifies the potential risk to the fetus

Precautions & Warnings

  • Not to be used on large open wounds or severely injured skin
  • Should not be used for the treatment of otitis external when the eardrum is perforated
  • Self-medication for deep or puncture wounds, animal bites, or serious burns should be advised to first consult a physician
  • Discontinue if the condition persists or worsens; should not be used for longer than 1 week unless directed by a physician

Use in Special Populations

  • Suitable for use in children at the same dose as adults, but the dose should be reduced in infants
  • Not recommended for use in neonates

Therapeutic Class

  • Ophthalmic and Topical antibacterial products

Storage Conditions

  • Keep all medicines out of reach of children
  • Store in a cool and dry place, protected from light

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