Tigilow 10 mg (Tablet)

Unit Price: ৳ 12.04 (3 x 10: ৳ 361.20)
Strip Price: ৳ 120.40

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Labaid pharma ltd
Also available as
Tigilow 20 mg tablet

Title

Tigilow 10 mg Tablet

Categories

  • Medicine
  • Cholesterol Medication
  • Statins

Description

Tigilow 10 mg Tablet is a selective inhibitor of HMG-CoA reductase and is used to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B), and triglyceride levels in various diseases. It is also used for the prevention of cardiovascular events and to reduce the risk of cardiac ischaemic events. The medicine is generally well-tolerated but may have side effects related to gastrointestinal discomfort and other rare side effects.

Brand

Tigilow

Strength

10 mg

Pack size

1 Strip of 10 Tablets

Manufacturer

Manufacturer Name

Price

100

Dimensions

  • Size: Small
  • Shape: Oval
  • Weight: Light

Color options

  • White

Active ingredient

Atorvastatin

Dosage form

Tablet

Indication

  • Reduction of total cholesterol and LDL cholesterol in patients with heterozygous and homozygous familial hypercholesterolaemia
  • Treatment of patients with elevated serum triglyceride levels in hypertriglyceridaemia
  • Prevention of cardiovascular events in patients with asymptomatic or mild to moderate symptomatic coronary artery disease

Pharmacology

  • Mechanism of action: Selective inhibitor of HMG-CoA reductase
  • Absorption: Rapidly absorbed after oral administration; maximum plasma concentrations occur within 1 to 2 hours.
  • Metabolism: Extensively metabolized to ortho- and parahydroxylated derivatives and various beta-oxidation products.
  • Excretion: Eliminated primarily in bile following hepatic and/or extra-hepatic metabolism.

Dosage administration

  • Recommended dose: 10 mg once daily
  • Max dose: 80 mg once daily
  • Dosage adjustment guidelines: Lipid levels should be analyzed within 2 to 4 weeks and dosage adjusted accordingly.

Interactions

  • Increased risk of myopathy with concurrent administration of certain drugs
  • Plasma concentrations affected when coadministered with antacids, colestipol, digoxin, erythromycin, oral contraceptives, or warfarin

Contraindications

  • Hypersensitivity to any component of the medication
  • Active liver disease or unexplained persistent elevations of serum transaminases
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

Side effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy lactation

  • Contraindicated during pregnancy: 1
  • Should not be used during breastfeeding: 1

Precautions warnings

  • Liver function tests should be performed periodically
  • Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected

Special populations

  • Geriatric: Plasma concentrations are higher in healthy elderly subjects
  • Pediatric: Pharmacokinetic data not available
  • Gender: No clinically significant difference in LDL-C reduction between men and women
  • Renal insufficiency: No influence on plasma concentrations or LDL-C reduction
  • Hemodialysis: Not expected to significantly enhance clearance
  • Hepatic insufficiency: Plasma concentrations are markedly increased in patients with chronic alcoholic liver disease

Overdose effects

No specific treatment available, should be treated symptomatically and supportive measures instituted

Therapeutic class

  • Anti-anginal & Anti-ischaemic drug
  • Statins

Storage conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

Chemical structure

  • Molecular formula: C33H35FN2O5
  • Image url: https://medex.com.bd/storage/res/g-res-92-atorvastatin-calcium-chemical-structure-vKDE8RIA4syu8MLTgdLW.svg

Commonly asked questions

  • Questions:
    • What is Tigilow 10 mg Tablet?
    • How should I take Tigilow 10 mg Tablet?
    • What are the uses of Tigilow 10 mg Tablet?
    • What are the Side Effects of Tigilow 10 mg Tablet?
    • What are the instructions for storage and disposal Tigilow 10 mg Tablet?
    • Is Tigilow 10 mg Tablet used for lowering cholesterol?
    • Will taking Tigilow 10 mg Tablet increase my risk of diabetes?
    • For how long do I need to take Tigilow 10 mg Tablet? Is it safe for long-term use?
    • Does Tigilow 10 mg Tablet cause weight loss?
    • Can I stop taking Tigilow 10 mg Tablet?
    • Does Tigilow 10 mg Tablet cause memory loss?
    • Does Tigilow 10 mg Tablet make you tired?
    • Can Tigilow 10 mg Tablet be prescribed to children?
    • Is Tigilow 10 mg Tablet a blood thinner?
  • Tips:
    • In general, Tigilow 10 mg Tablet is safe. It may cause diarrhea, gas, or an upset stomach. If any of these happen to you, take it with food.
    • Inform your doctor if you experience fatigue, muscle weakness, or muscle pain.
    • Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems.
    • Inform your doctor if you have kidney disease, liver disease, or diabetes before starting treatment with this medicine.
    • Do not take Tigilow 10 mg Tablet if you are pregnant, planning a pregnancy, or breastfeeding.

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