Cantrim 1% (Cream)
Medicine Details
Category | Details |
---|---|
Generic | Clotrimazole topical |
Company | Rephco pharmaceuticals ltd |
Indications
- Dermatomycoses due to dermatophytes
- Dermatomycoses due to yeasts
- Dermatomycoses due to moulds and other fungi
- Skin diseases showing superinfections with these fungi
- Interdigital mycoses (e.g. athlete's foot)
- Paronychias (associated with nail mycoses)
- Mycoses in skin folds
- Candida vulvitis
- Candida balanitis
- Pityriasis versicolor
- Erythrasma
Description
A broad-spectrum antifungal agent used for the treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, moulds, and bacteroids. Also active against certain gram-positive bacteria especially Staphylococci and Tricomonas. Alters the permeability of fungal cell walls by interfering with cell wall lipids.
Pharmacology
Acts primarily by damaging the permeability barrier in the cell membrane of fungi. Causes inhibition of ergosterol biosynthesis, an essential constituent of fungal cell membranes.
Dosage & Administration
Clotrimazole Cream should be thinly applied 2-3 times daily to the infected sites and rubbed in. Recommended duration of treatment varies depending on the disease. Clotrimazole topical solution should be applied sparingly to the affected areas and rubbed in gently, two or three times daily.
Interaction
No information is available.
Contraindications
Hypersensitivity to Clotrimazole.
Side Effects
Well tolerated when applied topically. Local irritation or burning sensation may occur in very few cases but these symptoms are not considered harmful.
Pregnancy & Lactation
Recommended for use in pregnancy only when considered necessary by the physician.
Therapeutic Class
Drugs for subcutaneous and mycoses, Topical Antifungal preparations
Storage Conditions
Keep below 25°C temperature, away from light and moisture. Keep out of the reach of children.