Dermasim 1% (Topical Solution)
20 ml bottle: ৳ 85.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clotrimazole topical |
| Company | Aci limited |
| Also available as |
Indications
- Treatment of dermatomycoses due to dermatophytes
- Treatment of dermatomycoses due to yeasts
- Treatment of dermatomycoses due to moulds and other fungi
- Treatment of skin diseases showing superinfections with these fungi
- Treatment of interdigital mycoses (e.g. athlete's foot)
- Treatment of paronychias associated with nail mycoses
- Treatment of mycoses in skin folds
- Treatment of Candida vulvitis
- Treatment of Candida balanitis
- Treatment of Pityriasis versicolor
- Treatment of erythrasma
Description
- Broad-spectrum antifungal agent
- Used for the treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, moulds, and bacteroids
- Active against certain gram-positive bacteria, especially Staphylococci and Tricomonas
- Alters the permeability of fungal cell walls
- Inhibition of ergosterol synthesis
- Mechanism of membrane damage unrelated to sterol synthesis
Pharmacology
- Damages the permeability barrier in the cell membrane of fungi
- Causes inhibition of ergosterol biosynthesis
- Inhibition of lanosterol 14-demethylase (CYP51)
- Depletion of intracellular calcium
- Blocking of calcium‐dependent potassium channels and voltage‐dependent calcium channels
Dosage & Administration
- Thinly applied 2-3 times daily to the infected sites and rubbed in
- Small amount of cream is usually sufficient for an area about the size of the palm
- Recommended duration of treatment for different conditions
- Preventive treatment for fungal infection of the feet
- Odorless and can be washed off
Interaction
- No information available
Contraindications
- Hypersensitivity to Clotrimazole
Side Effects
- Well tolerated with external application
- Systemic effects are not observed
- Local irritation or burning sensation may occur in very few cases
Pregnancy & Lactation
- Recommended for use in pregnancy only when considered necessary by the physician
Therapeutic Class
- Drugs for subcutaneous and mycoses
- Topical Antifungal preparations
Storage Conditions
- Keep below 25°C temperature
- Away from light & moisture
- Keep out of the reach of children