Fusten 1% (Cream)
10 gm tube: ৳ 35.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clotrimazole topical |
| Company | Kumudini pharma ltd |
Indications
- Treatment of dermatomycoses due to dermatophytes (e.g. Trichophyton species)
- Treatment of dermatomycoses due to yeasts (Candida species)
- Treatment of dermatomycoses due to moulds and other fungi
- Treatment of skin diseases showing superinfections with fungi
- Treatment of interdigital mycoses (e.g. athlete's foot)
- Treatment of paronychias (associated with nail mycoses)
- Treatment of mycoses in skin folds
- Treatment of Candida vulvitis
- Treatment of Candida balanitis
- Treatment of Pityriasis versicolor
- Treatment of erythrasma
Description
- Broad-spectrum antifungal agent
- Used for the treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, moulds, and bacteroids
- Active against certain gram-positive bacteria especially Staphylococci and Tricomonas
- Alters the permeability of fungal cell walls by interfering with cell wall lipids
- Inhibition of ergosterol synthesis at fungi static levels
Pharmacology
- Damages the permeability barrier in the cell membrane of fungi
- Causes inhibition of ergosterol biosynthesis
- Leads to dose-dependent inhibition of fungal growth
- Inhibits lanosterol 14-demethylase (CYP51)
- Inhibition of sarcoplasmic reticulum Ca^2+ ATPase
- Depletion of intracellular calcium
- Blocking of calcium‐dependent potassium channels and voltage-dependent calcium channels
Dosage & Administration
- Thinly applied 2-3 times daily to the infected sites and rubbed in
- Small amount of cream is usually sufficient for an area about the size of the palm
- Recommended duration of treatment for different conditions
- Preventing relapse in fungal infection of the feet
- Application of Clotrimazole topical solution
Interaction
- No information available
Contraindications
- Hypersensitivity to Clotrimazole
Side Effects
- Well tolerated when applied topically
- Local irritation or burning sensation may occur in very few cases
Pregnancy & Lactation
- Recommended for use in pregnancy only when considered necessary by the physician
Therapeutic Class
- Drugs for subcutaneous and mycoses
- Topical Antifungal preparations
Storage Conditions
- Keep below 25°C temperature
- Keep away from light & moisture