Trova 20 mg (Tablet)

Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Biopharma limited
Also available as
Trova 10 mg tablet

Title

Trova 20 mg Tablet

Categories

  • Cholesterol-lowering Medication
  • Cardiovascular Medication

Description

Trova 20 mg Tablet is a medication used to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B), and triglycerides levels. It is indicated for conditions such as familial hypercholesterolaemia, mixed dyslipidemia, hypertriglyceridemia, dysbetalipoproteinaemia, coronary artery disease, and hypercholesterolemia exacerbated by diabetes or renal transplantation.

Dosage

Available in 20 mg strength; maximum daily dose of 80 mg in adults; initial dose for children (10-18 years) is 10 mg once daily

Indications

  • Reduction of total cholesterol and LDL cholesterol
  • Treatment of elevated cholesterol and triglycerides
  • Reduction of cardiac ischaemic events
  • To reduce total and LDL-cholesterol concentrations

Mode of Action

Selective inhibitor of HMG-CoA reductase; lowers plasma cholesterol and lipoprotein levels by inhibiting cholesterol synthesis in the liver

Absorption

  • Rapid absorption after oral administration
  • Maximum plasma concentrations occur within 1 to 2 hours

Distribution

  • Mean volume of distribution is approximately 381 liters
  • 98% bound to plasma proteins

Metabolism

  • Extensively metabolized to ortho- and parahydroxylated derivatives
  • Metabolism by cytochrome P450 3A4

Excretion

  • Eliminated primarily in bile
  • Plasma elimination half-life is approximately 14 hours

Interaction

  • Risk of myopathy with concurrent administration of certain drugs
  • Effects with antacid, colestipol, digoxin, erythromycin, oral contraceptives, and warfarin

Contraindications

  • Hypersensitivity to any component
  • Active liver disease
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

Side Effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Not known whether excreted in human milk
  • Women taking the medication should not breastfeed their infants

Precautions & Warnings

  • Liver function tests should be performed before initiation of treatment
  • Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected

Use in Special Populations

  • Plasma concentrations are higher in healthy elderly subjects
  • No clinically significant difference in LDL-C reduction between men and women
  • Renal disease has no influence on plasma concentrations or LDL-C reduction

Storage Conditions

Keep in a dry place away from light and heat; keep out of the reach of children

Compound Summary

  • Molecular Formula: C33H35FN2O5
  • Chemical Structure: https://medex.com.bd/storage/res/g-res-92-atorvastatin-calcium-chemical-structure-vKDE8RIA4syu8MLTgdLW.svg

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Overdose Effects

Specific treatment not available; treat symptomatically and institute supportive measures; monitor liver function tests and serum CK levels

Common Questions

  • What is Trova 20 mg Tablet?: Used to avoid heart attacks and treat conditions such as Mixed Dyslipidemia and Hypertriglyceridemia
  • How should I take Trova 20 mg Tablet?: Taken by mouth once daily, with or without food
  • What are the uses of Trova 20 mg Tablet?: Treatment of Mixed Dyslipidemia, Hypertriglyceridemia, heart attacks, and Primary Hypercholesterolemia
  • What are the Side Effects of Trova 20 mg Tablet?: Possible side-effects include cough, muscle pain, breathing difficulty, and running nose
  • What are the instructions for storage and disposal Trova 20 mg Tablet?: Store at room temperature, away from heat and direct light; keep away from the reach of children and pets
  • Is Trova 20 mg Tablet used for lowering cholesterol?: Yes, it lowers cholesterol and triglycerides present in the blood
  • Will taking Trova 20 mg Tablet increase my risk of diabetes?: May affect blood sugar levels, so regular monitoring is important
  • For how long do I need to take Trova 20 mg Tablet? Is it safe for long-term use?: Take for the duration prescribed; considered safe for long term use if taken as directed
  • Does Trova 20 mg Tablet cause weight loss?: No studies report weight loss as a side effect
  • Can I stop taking Trova 20 mg Tablet?: Do not stop without informing your doctor; complete the full course of medication
  • Does Trova 20 mg Tablet cause memory loss?: Very rare side effect; consult a doctor if experienced
  • Does Trova 20 mg Tablet make you tired?: May make you feel tired; exact reason unknown
  • Can Trova 20 mg Tablet be prescribed to children?: Used by adults; caution exercised in children above 10 years
  • Is Trova 20 mg Tablet a blood thinner?: Does not cause thinning of the blood

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