Vass 20 mg (Tablet)

Unit Price: ৳ 20.10 (2 x 10: ৳ 402.00)
Strip Price: ৳ 201.00

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Sandoz a novartis division
Also available as
Vass 10 mg tablet

Title

Vass 20 mg Tablet

Categories

  • Medicine
  • Health
  • Pharmacology

Description

Vass is a selective inhibitor of HMG-CoA reductase used to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B), and triglycerides levels in various diseases when response to diet and non-pharmacological measures is inadequate. It is also indicated for the prevention of cardiovascular events, treatment of dysbetalipoproteinaemia, and more.

Dimensions

N/A

Color Options

  • White

Functions

  • Reduces total cholesterol and LDL cholesterol levels
  • Increases hepatic LDL receptors for enhanced uptake and catabolism of LDL

Materials

  • Atorvastatin

Technical Specifications

  • Absorption: Rapidly absorbed after oral administration, maximum plasma concentrations occur within 1 to 2 hours
  • Distribution: Mean volume of distribution is approximately 381 liters, 98% bound to plasma proteins
  • Metabolism: Extensively metabolized to ortho- and parahydroxylated derivatives and various beta-oxidation products
  • Excretion: Eliminated primarily in bile, mean plasma elimination half-life approximately 14 hours

Design Elements

  • Chemical Structure: C33H35FN2O5
  • Chemical Structure Image: URL

Usability Features

  • Administered as a single dose at any time of the day, with or without food
  • Lipid levels should be analyzed within 2 to 4 weeks after initiation

Dosage

  • Adults: 10 to 80 mg once daily
  • Children (10-18 years): Usually 10 mg once daily, increased if necessary
  • Instructions: Start with a standard cholesterol-lowering diet before receiving Atorvastatin and continue during treatment

Interaction

  • Concurrent Administration Risks:
    • Increased risk of myopathy with certain concurrent drugs
    • Plasma concentrations affected when coadministered with antacid, colestipol, digoxin, erythromycin, oral contraceptives, and warfarin

Contraindications

  • Hypersensitivity to any component
  • Active liver disease
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

Side Effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy & Lactation

  • Pregnancy: Contraindicated, no safety established, avoid use during pregnancy
  • Lactation: Not known whether excreted in human milk, avoid breastfeeding during use

Precautions & Warnings

Liver function tests should be performed before initiation of treatment and periodically thereafter, discontinue if markedly elevated CPK levels occur or myopathy is diagnosed or suspected

Use in Special Populations

  • Geriatric: Higher plasma concentrations in elderly subjects, greater LDL-lowering in elderly compared to younger adults
  • Pediatric: Pharmacokinetic data not available
  • Gender: No clinically significant difference in LDL-C reduction between men and women
  • Renal Insufficiency: No influence on plasma concentrations or LDL-C reduction, dose adjustment not necessary
  • Hepatic Insufficiency: Markedly increased plasma concentrations in patients with chronic alcoholic liver disease

Overdose Effects

Specific treatment not available, should be treated symptomatically and supportive measures instituted, extensive binding to plasma proteins limits effectiveness of hemodialysis

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

Keep in a dry place away from light and heat, keep out of the reach of children

Common Questions

  • What is Vass 20 mg Tablet?: Selective inhibitor of HMG-CoA reductase used to avoid heart attacks, treat Primary Hypercholesterolemia, Mixed Dyslipidemia, and Hypertriglyceridemia
  • How should I take Vass 20 mg Tablet?: Take by mouth once daily, at the same time each day, with or without food
  • What are the uses of Vass 20 mg Tablet?: Treatment of diseases like Mixed Dyslipidemia and Hypertriglyceridemia, as well as heart attacks and Primary Hypercholesterolemia
  • What are the Side Effects of Vass 20 mg Tablet?: Possible side-effects include cough, muscle pain, breathing difficulty, running nose
  • What are the instructions for storage and disposal Vass 20 mg Tablet?: Store at room temperature, away from heat and direct light, out of the reach of children and pets
  • Is Vass 20 mg Tablet used for lowering cholesterol?: Yes, it is used to lower cholesterol and triglycerides present in the blood

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