Perma 5% w/w (Cream)
15 gm tube: ৳ 24.07
Medicine Details
| Category | Details |
|---|---|
| Generic | Permethrin |
| Company | Alco pharma ltd |
Indications
- Treatment of scabies
- Treatment of crab lice infestations (Pediculosis)
- Suitable for family-wide treatment
Pharmacology
- Contains Permethrin, a pyrethroid
- Topical scabicidal agent
- Disrupts sodium channel current
- Leads to delayed repolarization & paralysis of pests
Pharmacokinetics
- Topical route of administration
- Limited systemic exposure or kinetics data available
- Presystemic metabolism in skin
- Less than 0.5% absorption within 48 hours
- Rapid metabolism and excretion
Dosage
- Recommended duration of treatment for different age groups
Administration
- Instructions for applying to adults and children over 2 years
- Instructions for applying to babies under 2 years
- Recommended duration for leaving the cream on
- Instructions for reapplication if necessary
Interaction
- Risk of exacerbating scabies infestation with corticosteroids for eczemodous reactions
Contraindications
- Hypersensitivity to pyrethroids or permethrin
- Recommendation for nursing staff to wear gloves to avoid irritation
Side Effects
- Skin discomfort after application
- Transient signs and symptoms of irritation
- Described sensations including burning, stinging, tingling, erythema, edema, eczema, rash, pruritis
Pregnancy & Lactation
- Use in pregnancy should follow medical advice
- Unknown excretion of permethrin in human milk
- Not recommended for nursing mothers
Precautions & Warnings
- Potential exacerbation of pruritus, edema & erythema
- Advice to avoid eye contact during application
- Instructions for immediate flushing with water if cream gets in the eyes
Therapeutic Class
- Parasiticidal preparations
Storage Conditions
- Recommendation for cool, dry storage away from light and out of reach of children